Insect growth regulator (IGR) activity of 52 substituted oxime ethers was evaluated against an important polyphagous lepidopteran pest, Spodoptera litura (F.) (Lepidoptera: Noctuidae). Several compounds produced symptoms comparable to exogenously applied juvenile hormone. Maximum IGR activity was exhibited by 4′-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3′-buten-2′(E)-ketoxime-N-O-alkyl ether with an ED50 (morphological) of 40 μg g−1 body weight, compared with 20 μg g−1 of juvenile hormone (JH) III. Two more compounds, namely, 4′-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3′-buten-2′(Z)-ketoxime-N-O-methyl propyl ether (ED50 of 192 μg g−1) and 4′-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3′-buten-2′(E)-ketoxime-N-O-pentyl ether (ED50 of 380 μg g−1) showed considerable IGR activity, whereas 4′-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3′-buten-2′(E)-ketoxime-N-O-pentyl ether was found to be acutely toxic to larvae (ED50 of 268 μg g−1). Three compounds used in this study also were synergized by piperonyl butoxide. Synergistic ratios ranged from 1.330 to 4.605. No significant ovicidal activity was obtained.
Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.