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Multinomial Logit Analysis of the Effects of Chemical Mixtures

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Uses of a multinomial logit model for investigations of chemical interactions were investigated. The probabilities of four types of effects when mixtures of benzoylphenylureas (BPUs; diflubenzuron or trillumuron) or a juvenile hormone analogue (JHA; methoprene) with selected pyrethroids (fenvalerate or permethrin) were compared. Bioassays were done on fourth- or sixth-instar western spruce budworm, Choristoneura occidentalis Freeman). When sprayed on fourth instars, mixtures of methoprene + fenvalerate, trillumuron + fenvalerate, and dillubenzuron + permethrin produced effects significantly different from those predicted by the hypothesis of additive effectiveness. When sprayed on sixth instars, only mixtures of the BPUs with fenvalerate produced effects significantly different from this hypothesis. We conclude that the multinomiallogit model may be useful to identify interactions between chemicals that merit biochemical investigation.

Document Type: Research Article

Publication date: December 1, 1991

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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