Synthesis and Structure-activity Studies on Aliphatic Carbamates and Thiocarbamates Toxic to Scabies Mites, Psoroptes spp. (Acari: Psoroptidae)

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In laboratory tests, dialkyl carbamates of types ROC(O)NHR′, RSC(O)NHR′, and ROC(S)NHR′ were found to be extremely toxic to Psoroptes spp., including P. ovis (Hering), the common scabies mite of cattle and sheep. Fifty-six compounds of these three types were lethal to P. cuniculi (Delafond) at 0.001 % AI in a tea bag assay. Molecular length, and not the position of the functional group, determined toxicity. Those compounds also tested against P. ovis had approximately equal activity for both species. Testing on rabbits or cattle with scabies showed activity comparable to that of toxaphene, the commercial standard.

Document Type: Research Article

Publication date: June 1, 1985

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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