Factors Involved in the Selective Toxicity of Mephosfolan to Southern Armyworms and Tobacco Budworms (Lepidoptera: Noctuidae)

Authors: Hollingshaus, J. G.; Sander, G.; Little, R. J.

Source: Journal of Economic Entomology, Volume 77, Number 6, December 1984 , pp. 1393-1399(7)

Publisher: Entomological Society of America

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Mephosfolan rapidly penetrated the cuticle of Spodoptera eridania (Cramer); from 35 to 40% of the applied dose was recovered in the tissues and from 60 to 65% was recovered in the external rinse 3 h after treatment. After 24 h, more than 70% of the dose was excreted, whereas from 10 to 15% remained in the tissues. In contrast, from 80 to 85% of the applied dose was recovered in the external rinse of Heliothis virescens (F.) after 3 h; from 75 to 80% was recovered after 24 h. Less than 10% of the dose was recoverable in tissues of H. virescens at any given time. This suggests differences in penetration account for much of the selective toxicity of mephosfolan to S. eridania. The actual concentration of mephosfolan in the tissues of each species after topical application of an LD25 indicated that S. eridania is approximately 4-fold more sensitive to mephosfolan than is H. virescens. Since an unextractable residue was associated with precipitable protein in the tissues of both species, at least part of the mephosfolan molecule might be bound to protein. A possible explanation for this binding is described with respect to the development of resistance.

Document Type: Research Article

Publication date: December 1, 1984

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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