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The toxicity of binary mixtures of formamidines and pyrethroids to Tetranychus urticae Koch was investigated and compared with the toxicity of their individual components. A synergistic interaction was observed with 85 of the 104 formamidines examined in binary mixtures with cypermethrin; 29 of these improved toxicity 5-fold or greater. With regard to the different pyrethroids, there was evidence for suggesting that formamidine synergism generally was greatest with cypermethrin and deltamethrin, intermediate with fluvalinate, flucythrinate, and fenpropathrin, and least with fenvalerate and permethrin. The four best overall pyrethroid synergists were N'-(2,4-dimethylphenyl)-N-methy 1-N-(pheny Ithio)formamidine (Upjohn-42564), N' -(2,4,6,-trimeth yIpheny1)-N,N-dimeth yIformamidine, N' -(3,4-methylenedioxypheny 1)-N ,N -dimethylformamidine, and chlordimeform. The greatest synergism of cypermethrin was a 24-fold enhancement by the methylenedioxyphenyl formamidine; synergism by this formamidine of other pyrethroids ranged from 8.9-fold to only 2.5-fold. Structure-activity relationship studies clearly indicated that the ability of formamidines to effect synergism of pyrethroids was not inextricably associated with their lethality in spider mites. Thus, highly active synergists included some formamidines that were directly lethal to spider mites and some that demonstrated little, if any, direct toxicity to this organism.
Document Type: Research Article
Publication date: February 1, 1984
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Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.