When white mice were exposed to infestation by (1) transplanting 1st-stage, 2- to 4-month-old larvae of Hypoderma lineatum (de Villers) from the esophagus of cattle to subdermal sites in mice or (2) by allowing female flies to lay fertile eggs on the hairs of mice, the larvae migrated to the thoracic or abdominal cavity of the host mice where the survival and growth of the larvae were enhanced by injections of rabbit antimouse lymphocyte serum to the mice. Also, in mice so treated, the midgut of larvae appeared morphologically normal; in untreated mice, the midgut epithelium appeared abnormal. The extent of coverage and the cellular composition of host capsular tissue adhering to larvae did not seem to be related to survival or growth of larvae.
Document Type: Research Article
Publication date: April 16, 1973
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