Chemosterilization of Male House Flies1 with Dithiazolium Compounds and with Tetramethyldithiobiuret2,3

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Abstract:

In structure-activity studies the sterilizing activity of 3-5-bis(dimethylamino)-1,24-dithiazolium chloride in made Musca domestica L. has been extended to homologues with diethylamino, pyrrolidinyl, piperidino, and morpholino groups in the 3 and/or 5 positions. Of the 12 active compounds, 9 had similar SD30 about 5 moles X 10-9/♂ which was somewhat higher than that of tepa but lower than those of hempa and hemel. 1,1,5,5-Tetramethyl-2-4 dithiobiuret, a representative of a new class of male sterilants, was compared in feeding and injection tests with its cyclizatioin product, 3-5- bis(dimethylamino) 1,2,4-dithiazolium chloride. Both compounds had similar sterilizing and toxic properties.

Document Type: Research Article

Publication date: April 1, 1972

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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