Biochemical Effect of Metepa on House Fly Eggs1,2

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Nucleic acids synthesis during the period of embryonic development of eggs of Musca domestica L. from normal and chemosterilized adult house flies has been studied. These studies indicated that metepa was found to interfere with the high molecular weight of DNA synthesis during the period of embryonic development of the house fly eggs. In normal eggs, DNA increased many fold after I hour of oviposition. The nucleic acids from the eggs of normal and chemosterilized house flies were studied by methylated albumin Kielseguhr (MAK) column c11romatography. Absence of a DNA peak for the sterilized eggs in the MAK column chromatography substantiates lack of DNA synthesis in the chemosterilized eggs as determined by the diphenylamine method. Synthesis of LDH in the normal eggs followed the growth curve of DNA. LDH activity was higher in normal eggs than it was in chemosterilized eggs. In contrast, activity of G-6-PDH increased when measured in the chemosterilized eggs.

Document Type: Research Article

Publication date: April 1, 1972

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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