Induction by DDT and Dieldrin of Insecticide Metabolism by House Fly1 Enzymes2,3

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House fly, Musca domestica L., strains resistant to chlorinated insecticides were fed high dietary levels of DDT or dieldrin ad lib. Homogenates prepared from the abdomens of treated flies showed significantly higher ability to metabolize 5 insecticide substrates than similar homogenates from flies fed untreated diets. The increases in metabolism ranged from 20 to 150%. The results show that metabolism of insecticides is an inducible phenomenon in house flies, much as it is in mammals

Document Type: Research Article

Publication date: August 1, 1970

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