Teratogenic Effects of a Tranquilizer, Trifluoperazine Dihydrochloride on the Yellow-Fever Mosquito1


Source: Journal of Economic Entomology, Volume 60, Number 6, December 1967 , pp. 1650-1655(6)

Publisher: Entomological Society of America

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Adults obtained from larvae of the yellow-fever mosquito, Aedes aegypti (L.), treated with dilute solutions of a tranquilizer, trifluoperazine dihydrochloride (2 to 75 ppm), indicate that the chemical has teratogenic effects on the insect. Some of the ensuing adults showed morphological abnormalities similar to those of recognized mutants which have been found in nature or produced as a result of thermal stress in the laboratory. In others, some of the head structures were either deformed or fused, and the normal functioning of the mouthparts became impossible. At the highest concentration tested (75 ppm) the eclosion of the imagoes was also affected. It is suggested that chemicals having similar properties, which are per se nontoxic, can be used effectively for the regulation of insect populations.

Document Type: Research Article

Publication date: December 1, 1967

More about this publication?
  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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