Comparative Fate of the Geometric Isomers of Phosphamidon in Plants and Animals1,2
Authors: BULL, D. L.; LINDQUIST, D. A.; GRABBE, R. R.
Source: Journal of Economic Entomology, Volume 60, Number 2, April 1967 , pp. 332-341(10)
Publisher: Entomological Society of America
Abstract:The fates of the cis and trans isomers of phosphamidon in plants and animals were determined by using radiometric and other procedures. The biological half-lives of toxic forms of the 2 isomers were very short in plants and animals and of comparable duration. Although both isomers were converted to similar oxidative and hydrolytic metabolites, the rates of formation were somewhat different; the faster rate of oxidative N-dealkylation of cis phosphamidon in all biological systems was particularly apparent. Not only were the trans isomers of phosphamidon and its N-deethyl derivative substantially more toxic to adult boll weevils Anthonomus grandis Boheman. and house flies, Musca domestica L., than were the cis isomers, but they also were significantly more potent inhibitors of acetyl cholinesterase in the insects. Combinations of sesamex with cis and trails phosphamidon and N-deethyl derivatives caused a substantial increase ill the toxicity of all compounds to boll weevils, particularly the cis isomers.
Document Type: Research Article
Publication date: April 1, 1967
- Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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