The Chemosterilant Activity of Some Substituted Phenyl Esters of Aziridine-1-carboxylic Acid

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Chemosterilant tests using adult Musca domestica L. as the test insect were conducted with substituted phenyl esters of aziridine-1-carboxylic acid. The compounds were administered mixed with sugar, and 2 were found to show significant sterilant activity: they were the 4-chloro-3-methyl and the 2-chloro, 4,5-dimethyl phenyl esters. The latter compound was the more active and sterilized males but not females. It was also the least insecticidal.

A higher level of sterility occurred when compounds were fed to a population of mixed sexes, than when sexes were treated separately and then mixed. N-methyl carbamate analogues of these materials were highly insecticidal. This phenomenon suggests that in this instance these ester groups can act as carriers for either insecticides or sterilants. Both the sterilant compounds were of limited stability.

Document Type: Research Article

Publication date: April 1, 1965

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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