Partial Characterization of the in Vivo Metabolites of DDT-C14 in Triatoma infestans1

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Triatoma infestans third-instar larvae were topically treated with DDT-C14 and Kelthane┬«-C14 (1,1-bis (P-chlorophenyl)- 2-2-2-trichloroethanol). After 72 hours of DDT-intoxication, 2 DDT-metabolites were detected (metabolites no. 2 and no. 3), while only 1 was found from Kelthane thane after 10 days. DDT metabolite no. 3 was characterized by paper chromatography, chemical reactions, and the UV spectrum at the microchemical range. The results obtained indicate that metabolite no. 3 corresponds to Kelthane. Although no definite identification of DDT-metabolite no. 2 and the Kelthane-metabolite was possible, the available evidence suggests that they have the same structure. It is suggested that Kelthane is the precursor of DDT-metabolite no. 2, indicating that production of DDT-polar metabolites in Triatoma infestans follows the sequence DDT → Kelthane →metabolite no. 2.

Document Type: Research Article

Publication date: December 1, 1964

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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