The toxicity of 40 substituted phenyl N-methylearbamates to the house fly, Musca domestica L., was re-evaluated with piperonyl butoxide as a synergist. There was no correlation between house fly toxicity and fly brain anticholinesterase activity when the carbonate was used alone. In general, the use of piperonyl butoxide with the carbonate increased the toxicity to levels which parallel anticholinesterase activity. An approximately linear relationship between the logarithm of toxicity and cholinesterase inhibition was obtained. The data support previous suggestions that variability in the toxicity of carbonates used alone is due to different detoxication rates in the insect.
Document Type: Research Article
Publication date: June 1, 1962
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Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.