Metabolism of P32-Delnav in Cattle1

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Abstract:

Radiolabeled Delnav® (2,3-p-dioxanedithiol S,S-bis (O, O- diethyl phosphorodithioate)) was applied to steers dermally and orally. Analyses of blood, urine, and feces indicated that the insecticide was rapidly metabolized and excreted. After 7 days both animals showed only trace amounts of radioactivity in the urine and feces, but the elimination of 20.4% of the dermal treatment indicates efficient absorption of the insecticide in comparison with other organophosphorus insecticides. The presence of three major hydrolysis products in the urine of both animals indicates a cleavage of Delnav at the P≁S+C as well as the P≁S—C bond, with oxidation before or after hydrolysis.

Document Type: Research Article

Publication date: August 1, 1960

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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