Toxicity of Organic Phosphorus Insecticides to Horses1

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Tests were made on 48 horses to find the optimal dosage of some organic phosphorus insecticides for use against horse bots. (Gasterophilidae). The animals were treated with Co-Ral® (O-(3-chloro-4-methyJumbelliferone) O, O-diethyl phosphorothioate), dimethoate, DOWCO I05® (O-methyl O-(4-tert-butyl chlorophenyl) ethylphosphoramidothioate), DOWCO I09® (O- (4-tert butyl-2-chlorophenyl) O-methyl methylphosphoramidotioate), ronnel, Ruelene® (4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate), DDVP, and Dipterex® (dimethyl 2,2,2-trichloro-1-hydroxyethyl phosphonntc). The insecticides dis were administered by stomach tube, by feeding, and by intramuscular injection. For 7 days until sacrifice, thc horses were observed frequently and checked for whole blood cholinesterase activity. Although six of the animals showed signs of toxicity during the observation period, only one showed gastrointestinal congestion at necropsy. Fourteen horses owned by cooperating ranchers were treated with Dipterex in feed, with no harmful effect. The problems of determining poisoning from phosphorus insecticides are discussed.

Document Type: Research Article

Publication date: August 1, 1960

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