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Methylenedioxyphenyl Derivatives as Synergists for Carbamate Insecticides on Susceptible, DDT-, and Parathion-resistant House Flies1

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2-(2-ethoxyethoxy)ethyl 3,4-methlylenedioxyphenyl acetal of acetaldehyde (sesamex) and 3,4-methylenedioxyphenyl benzenesulfonate were found to be active synergists for four carbamate insecticides against susceptible, DDT, and parathionresistant house flies (Musca domestica L.). In contrast to the usual ratios of synergist to insecticide, in this study, insecticide/ synergist ratios higher than 1.0 were used. Cross resistance and levels of tolerance to the carbamate insecticides by DDT- and parathion-resistant flies were determined. Studies of the in vitro inhibition of human blood plasma and fly head cholinesterases have shown that with the exception of Sevin® (1-naphthyl-N-methyl carbamate), the carbamates studied are less active inhibitors for fly head cholinesterases than for human plasma.

Document Type: Research Article

Publication date: April 1, 1960

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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