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The persistence and metabolism of Diazinon®,(O,O-diethyl O-(2-isopropyl-4-methyl-6-pyrimidinyl)phosphorothioated) dimethoate, parathion, and acethion (O,O-diethyl S-carboethoxy-methyl phosphorodithioate) have been studied in the mouse, American cockroach (Periplaneta americana (L.)), and house fly (Musca domestica L.). The results have been used to explain the selective toxicity of three of these compound toward insects as compared with mamamals. For Diazinon, selectivity is attributed to high levels of oxygen analog in the susceptible species. For dimethoate and acethion, selectivity is attributed to a persistence of unaltered parent compound in the whole body. Small differences were found in Diazinon absorption and metabolism by normal and Diazinon-resistant house flies.
Document Type: Research Article
Publication date: February 1, 1960
More about this publication?
Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.