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The Penetration of Piperonyl Butoxide as a Synergist and as an Antagonist in Musca domestica L.1

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Penetration studies were made on 4-day-old male house flies (Musca domestica L) with SevinĀ® (1-naphthyl-N-methyl carbamate) and piperonyl butoxide as a synergist, and malathion and piperonyl butoxide as an antagonist. Topical applications were made and groups of 100 flies were held for four time intervals, 6, 12, 18, and 24 hours, then extracted externally and internally. Companion treatments of piperonyl butoxide alone were extracted at those time intervals. The extracts were evaporated and the methylenedioxyphenyl color complex developed and read at 660 m. The rates of piperonyl butoxide penetration alone and with the toxicant were generally the same. A difference in the percentage of penetration and probably metabolism was observed between the two different levels of piperonyl butoxide, the lower level penetrating more rapidly percentagewise than the higher concentration. The penetration rate of piperonyl butoxide does not appear to determine its role as a synergist or antagonist.

Document Type: Research Article

Publication date: February 1, 1960

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  • Journal of Economic Entomology is published bimonthly in February, April, June, August, October, and December. The journal publishes articles on the economic significance of insects and is divided into the following sections: apiculture & social insects; arthropods in relation to plant disease; forum; insecticide resistance and resistance management; ecotoxicology; biological and microbial control; ecology and behavior; sampling and biostatistics; household and structural insects; medical entomology; molecular entomology; veterinary entomology; forest entomology; horticultural entomology; field and forage crops, and small grains; stored-product; commodity treatment and quarantine entomology; and plant resistance. In addition to research papers, Journal of Economic Entomology publishes Letters to the Editor, interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
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