Chemistry & Biology

Tools for Nanoscience at McGill University - Sometimes Smaller Is Better
pp. 1-2(2)

Grafting Miniature DNA Binding Proteins
pp. 3-4(2)
Author: Pflum M.K.H.

Don't Classify Polyketide Synthases
pp. 4-6(3)
Author: Muller R.

Breaking Up Is Easy To Do (If You're a DNA Enzyme that Cleaves RNA)
pp. 7-8(2)
Author: Silverman S.K.

Aureolic Acids - Similar Antibiotics with Different Biosynthetic Gene Clusters
pp. 8-10(3)
Author: O'Connor S.

Unraveling the Pathway of Lipoic Acid Biosynthesis
pp. 10-12(3)
Author: Booker S.J.

Profound Insights into Squalene Cyclization
pp. 12-14(3)
Author: Poralla K.

New Probes for Microtubule Dynamics
pp. 14-16(3)
Authors: Peters U.; Kapoor T.M.

Targeting FOXO Kills Two Birds with One Stone
pp. 16-18(3)
Authors: Wang W.; El-Deiry W.S.

Orthogonal Base Pairs Continue to Evolve
pp. 18-20(3)
Author: Bergstrom D.E.

Biosynthesis of the Antitumor Chromomycin A₃ in Streptomyces griseus - Analysis of the Gene Cluster and Rational Design of Novel Chromomycin Analogs
pp. 21-32(12)
Authors: Menendez N.; Nur-e-Alam M.; Brana A.F.; Rohr J.; Salas J.A.; Mendez C.

Leinamycin Biosynthesis Revealing Unprecedented Architectural Complexity for a Hybrid Polyketide Synthase and Nonribosomal Peptide Synthetase
pp. 33-45(13)
Authors: Tang G.-L.; Cheng Y.-Q.; Shen B.

Site-Specific Incorporation of a Photo-Crosslinking Component into RNA by T7 Transcription Mediated by Unnatural Base Pairs
pp. 47-55(9)
Authors: Kimoto M.; Endo M.; Mitsui T.; Okuni T.; Hirao I.; Yokoyama S.

Dinucleotide Junction Cleavage Versatility of 8-17 Deoxyribozyme
pp. 57-67(11)
Authors: Cruz R.P.G.; Withers J.B.; Li Y.

Controlling the DNA Binding Specificity of bHLH Proteins through Intramolecular Interactions
pp. 69-77(9)
Authors: Turner E.C.; Cureton C.H.; Weston C.J.; Smart O.S.; Allemann R.K.

Cloning, Sequencing, and Functional Analysis of the Biosynthetic Gene Cluster of Macrolactam Antibiotic Vicenistatin in Streptomyces halstedii
pp. 79-86(8)
Authors: Ogasawara Y.; Katayama K.; Minami A.; Otsuka M.; Eguchi T.; Kakinuma K.

Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tu4055 - Cluster Analysis and Assignment of Functions
pp. 87-97(11)
Authors: Olano C.; Wilkinson B.; Sanchez C.; Moss S.J.; Sheridan R.; Math V.; Weston A.J.; Brana A.F.; Martin C.J.; Oliynyk M.; Mendez C.; Leadlay P.F.; Salas J.A.

Design, Synthesis, and Characterization of Urokinase Plasminogen-Activator-Sensitive Near-Infrared Reporter
pp. 99-106(8)
Authors: Law B.; Curino A.; Bugge T.H.; Weissleder R.; Tung C.-H.

Biosynthetic Gene Cluster of the Glycopeptide Antibiotic Teicoplanin - Characterization of Two Glycosyltransferases and the Key Acyltransferase
pp. 107-119(13)
Authors: Li T.-L.; Huang F.; Haydock S.F.; Mironenko T.; Leadlay P.F.; Spencer J.B.

Conversion of Squalene to the Pentacarbocyclic Hopene
pp. 121-126(6)
Authors: Reinert D.J.; Balliano G.; Schulz G.E.

Binding of High-Mannose-Type Oligosaccharides and Synthetic Oligomannose Clusters to Human Antibody 2G12 - Implications for HIV-1 Vaccine Design
pp. 127-134(8)
Authors: Wang L.-X.; Ni J.; Singh S.; Li H.

Identification of a Novel Protein Regulating Microtubule Stability through a Chemical Approach
pp. 135-146(12)
Authors: Wignall S.M.; Gray N.S.; Chang Y.-T.; Juarez L.; Jacob R.; Al Burlingame; Schultz P.G.; Heald R.