Chemistry & Biology

Resisting resistance: new chemical strategies for battling superbugs
pp. 127-132(6)
Author: Wright G.D.

The ribosome - a macromolecular machine par excellence
pp. 133-141(9)
Author: Frank J.

Send in the gas - NicOx S.A.
pp. 142-143(2)
Author: Wells W.A.

Elsewhere in biology
pp. 147-151(5)

Dipeptide formation on engineered hybrid peptide synthetases
pp. 373-384(12)
Authors: Doekel S.; Marahiel M.A.

Brevetoxin derivatives that inhibit toxin activity
pp. 385-393(9)
Authors: Purkerson-Parker S.L.; Fieber L.A.; Rein K.S.; Podona T.; Baden D.G.

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway
pp. 395-403(9)
Authors: Brautaset T.; Sekurova O.N.; Sletta H.; Ellingsen T.E.; Strom A.R.; Valla S.; Zotchev S.B.

Tagging DNA mismatches by selective 2'-amine acylation
pp. 405-410(6)
Authors: John D.M.; Weeks K.M.

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors
pp. 411-422(12)
Authors: Knockaert M.; Gray N.; Damiens E.; Chang Y.-T.; Grellier P.; Grant K.; Fergusson D.; Mottram J.; Soete M.; Dubremetz J.-F.; Le Roch K.; Doerig C.; Schultz P.; Meijer L.

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
pp. 423-432(10)
Authors: Wei Y.; Fox T.; Chambers S.P.; Sintchak J.; Coll J.T.; Golec J.M.; Swenson L.; Wilson K.P.; Charifson P.S.

Simulated molecular evolution in a full combinatorial library
pp. 433-441(9)
Authors: Illgen K.; Enderle T.; Broger C.; Weber L.

Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates
pp. 443-452(10)
Authors: Hervio L.S.; Coombs G.S.; Bergstrom R.C.; Trivedi K.; Corey D.R.; Madison E.L.