A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction

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Keywords: Cytochrome P450 1A1; Ethoxyresorufin-O-demethylation activity; Methods; Rat; Reporter-gene system; Safety pharmacology; Western blotting

Document Type: Research Article

DOI: http://dx.doi.org/10.1016/S1056-8719(02)00222-8

Affiliations: Department of Exploratory Drug Discovery, Schering-Plough Research Institute, D209, K15-2700, 07033, Kenilworth, NJ, USA

Publication date: May 1, 2002

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