Bioorganic and Medicinal Chemistry

Evaluation of [¹⁸F]VUF 5000 as a potential PET ligand for brain imaging of the histamine H₃ receptor
pp. 1761-1767(7)
Authors: Windhorst A.D.; Timmerman H.; Klok R.P.; Menge W.M.P.B.; Leurs R.; Herscheid J.D.M.

Stereoelectronic features of the cinchona alkaloids determine their differential antimalarial activity
pp. 1769-1774(6)
Authors: Karle J.M.; Bhattacharjee A.K.

Melanocyte-directed enzyme prodrug therapy (MDEPT): development of a targeted treatment for malignant melanoma
pp. 1775-1780(6)
Authors: Jordan A.M.; Khan T.H.; Osborn H.M.I.; Photiou A.; Riley P.A.

Combinatorial discovery process yields antimicrobial peptoids
pp. 1781-1785(5)
Authors: Ng S.; Goodson B.; Ehrhardt A.; Moos W.H.; Siani M.; Winter J.

Heterocyclic analogues of l-citrulline as inhibitors of the isoforms of nitric oxide synthase (NOS) and identification of N-(4,5-dihydrothiazol-2-yl)ornithine as a potent inhibitor
pp. 1787-1796(10)
Authors: Ulhaq S.; Chinje E.C.; Naylor M.A.; Jaffar M.; Stratford I.J.; Threadgill M.D.

Direct solid-phase synthesis of octreotide conjugates - precursors for use as tumor-targeted radiopharmaceuticals
pp. 1797-1803(7)
Authors: Hsieh H.-P.; Wu Y.-T.; Chen S.-T.; Wang K.-T.

Molecular modeling of the dopamine D₂ and serotonin 5-HT_1A receptor binding modes of the enantiomers of 5-OMe-BPAT
pp. 1805-1820(16)
Authors: Homan E.J.; Wikstrom H.V.; Grol C.J.

Semisynthesis and cytotoxicity of amino acetogenins and derivatives
pp. 1821-1826(6)
Authors: Duret P.; Hocquemiller R.; Gantier J.-C.; Figadere B.

Synthesis of novel progestin-rhenium conjugates as potential ligands for the progesterone receptor
pp. 1827-1835(9)
Authors: Wust F.; Skaddan M.B.; Leibnitz P.; Spies H.; Katzenellenbogen J.A.; Johannsen B.

Synthesis and antagonistic activity at muscarinic receptor subtypes of some 2-carbonyl derivatives of diphenidol
pp. 1837-1844(8)
Authors: Varoli L.; Angeli P.; Burnelli S.; Marucci G.; Recanatini M.

Analogues of 1-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridin -11-yl)piperidine as inhibitors of farnesyl protein transferase
pp. 1845-1855(11)
Authors: Afonso A.; Weinstein J.; Kelly J.; Wolin R.; Rosenblum S.B.; Connolly M.; Guzi T.; James L.; Carr D.; Patton R.; Bishop W.R.; Kirshmeier P.; Liu M.; Heimark L.; Chen K.J.; Nomeir A.A.

Synthesis and investigation of glycosylated mono- and diarylporphyrins for photodynamic therapy
pp. 1857-1865(9)
Authors: Schell C.; Hombrecher H.K.

Chemoenzymatic synthesis and antitumor promoting activity of 6'- and 3-esters of 2-O--d-glucosylglycerol - Asymmetry
pp. 1867-1871(5)
Authors: Colombo D.; Compostella F.; Ronchetti F.; Scala A.; Toma L.; Tokuda H.; Nishino H.

Synthesis and binding properties of photoactivable biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein
pp. 1873-1880(8)
Authors: Teodori E.; Ettori D.; Garnier-Suillerot A.; Gualtieri F.; Manetti D.; Novella Romanelli M.; Scapecchi S.

Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains
pp. 1881-1890(10)
Authors: Buijsman R.C.; Basten J.E.M.; Dreef-Tromp C.M.; van der Marel G.A.; van Boeckel C.A.A.; van Boom J.H.

Novel Cobalt Complex Inhibitors of Mitochondrial Calcium Uptake
pp. 1891-1896(6)
Authors: Unitt J.F.; Boden K.L.; Wallace A.V.; Ingall A.H.; Coombs M.E.; Ince F.

Biomimetic degradation of lignin and lignin model compounds by synthetic anionic and cationic water soluble manganese and iron porphyrins
pp. 1897-1905(9)
Authors: Crestini C.; Saladino R.; Tagliatesta P.; Boschi T.

Anti-AIDS agents. Part 36:¹ 17-carboxylated steroids as potential anti-HIV agents
pp. 1907-1911(5)
Authors: Xia P.; Yang Z.-Y.; Xia Y.; Zheng Y.-Q.; Cosentino L.M.; Lee K.-H.

Imidazole substituted biphenyls: A new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer
pp. 1913-1924(12)
Authors: Wachall B.G.; Hector M.; Zhuang Y.; Hartmann R.W.

Synthesis and biological evaluation of 2-methoxy- and 2-Methylthio-6-[(2'-alkylamino)ethyl]-4(3H)-pyrimidinones with anti-rubella virus activity
pp. 1925-1931(7)
Authors: Botta M.; Occhionero F.; Nicoletti R.; Mastromarino P.; Conti C.; Magrini M.; Saladino R.

Synthesis and antifungal activity of coumarins and angular furanocoumarins
pp. 1933-1940(8)
Authors: Sardari S.; Mori Y.; Horita K.; Micetich R.G.; Nishibe S.; Daneshtalab M.

Imidazole-containing amino acids as selective inhibitors of nitric oxide synthases
pp. 1941-1951(11)
Authors: Lee Y.; Martasek P.; Roman L.J.; Masters B.S.S.; Silverman R.B.

The synthesis and antibacterial activity of totarol derivatives. part 1: modifications of ring-C and pro-drugs
pp. 1953-1964(12)
Authors: Evans G.B.; Furneaux R.H.; Gravestock M.B.; Lynch G.P.; Scott G.K.

Synthesis and deconvolution of the first combinatorial library of glycosidase inhibitors
pp. 1965-1971(7)
Authors: Lohse A.; Jensen K.B.; Lundgren K.; Bols M.

Lipase-catalysed regio- and enantioselective deacetylation of 2,4-diacetoxyphenyl alkyl ketones
pp. 1973-1977(5)
Authors: Prasad A.K.; Pati H.N.; Azim A.; Trikha S.; Poonam

tRNA^Phe binds aminoglycoside antibiotics
pp. 1979-1991(13)
Authors: Kirk S.R.; Tor Y.

Modulating pyridoxamine-mediated transamination through a motif peptide scaffold
pp. 1993-2002(10)
Authors: Shogren-Knaak M.A.; Imperiali B.

Oligosaccharides corresponding to the regular sequence of heparin: chemical synthesis and interaction with FGF-2
pp. 2003-2012(10)
Authors: Tabeur C.; Mallet J.-M.; Bono F.; Herbert J.-M.; Petitou M.; Sinay P.

In vitro cytotoxicity of 5-aminosubstituted 20(S)-camptothecins. part 1
pp. 2013-2020(8)
Authors: Subrahmanyam D.; Sarma V.M.; Venkateswarlu A.; Sastry T.V.R.S.; Kulakarni A.P.; Srinivasa Rao D.; Krishna Reddy K.V.S.R.

CH/ interaction in the conformation of peptides. A database study^&unknown;
pp. 2021-2026(6)
Authors: Umezawa Y.; Tsuboyama S.; Takahashi H.; Uzawa J.; Nishio M.

Chemical modification of apomorphine to discover ligands: 6H-dibenzo[b,d]pyran and carbazole analogues
pp. 2027-2035(9)
Authors: Nakazato A.; Sekiguchi Y.; Ohta K.; Chaki S.; Okuyama S.

Synthesis and evaluation of homofarnesoyl-substituted CAAX-peptidomimetics as farnesyltransferase inhibitors and antiproliferative agents
pp. 2037-2045(9)
Authors: Schlitzer M.; Sattler I.; Dahse H.-M.

Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, ganoderma lucidum
pp. 2047-2052(6)
Authors: Mizushina Y.; Takahashi N.; Hanashima L.; Koshino H.; Esumi Y.; Uzawa J.; Sugawara F.; Sakaguchi K.

Synthesis of an artificial glycoconjugate polymer carrying P^k-antigenic trisaccharide and its potent neutralization activity against Shiga-like toxin
pp. 2053-2062(10)
Authors: Dohi H.; Nishida Y.; Mizuno M.; Shinkai M.; Kobayashi T.; Takeda T.; Uzawa H.; Kobayashi K.

Structure-activity relationship of HIV-1 protease inhibitors containing -hydroxy--amino acids. Detailed study of P₁ site
pp. 2063-2072(10)
Authors: Takashiro E.; Hayakawa I.; Nitta T.; Kasuya A.; Miyamoto S.; Ozawa Y.; Yagi R.; Yamamoto I.; Shibayama T.; Nakagawa A.; Yabe Y.

Mechanism of hemolysis and erythrocyte transformation caused by lipogrammistin-A, a lipophilic and acylated cyclic polyamine from the skin secretion of soapfishes (Grammistidae)
pp. 2073-2081(9)
Authors: Kobayashi Y.; Onuki H.; Tachibana K.

Resolution, molecular structure and biological activities of the d- and l-enantiomers of potent anti-implantation agent, dl-2-[4-(2-Piperidinoethoxy)phenyl]-3-phenyl-2H-1-benzopyran
pp. 2083-2090(8)
Authors: Hajela K.; Pandey J.; Dwivedy A.; Dhar J.D.; Sarkhel S.; Maulik P.R.; Velumurugan D.

Mechanism of biochemical action of substituted 4-Methylbenzopyran-2-ones. Part 5: Pulse radiolysis studies on the antioxidant action of 7,8-diacetoxy-4-methylcoumarin
pp. 2091-2094(4)
Authors: Raj H.G.; Parmar V.S.; Jain S.C.; Priyadarsini K.I.; Mittal J.P.; Goel S.; Das S.K.; Sharma S.K.; Olsen C.E.; Wengel J.

Synthesis and antitumor activity of goniofufurone analogues
pp. 2095-2103(9)
Authors: Mereyala H.B.; Gadikota R.R.; Joe M.; Arora S.K.; Dastidar S.G.; Agarwal S.

design and synthesis of a novel series of HIV-1 protease inhibitors
pp. 2105-2114(10)
Authors: Takashiro E.; Nakamura Y.; Miyamoto S.; Ozawa Y.; Sugiyama A.; Fujimoto K.

Synthesis and biology of 3'-N-acyl-N-debenzoylpaclitaxel analogues
pp. 2115-2119(5)
Authors: Roh E.J.; Song C.E.; Kim D.; Pae H.-O.; Chung H.-T.; Lee K.S.; Chai K.-b.; Lee C.O.; Un Choi S.

Corrigendum to ''dolichylpyrophosphate oligosaccharides: large-scale isolation and evaluation of oligosaccharyltransferase substrates'' [Bioorg. Med. Chem. 7 (1999) 441-447]
pp. 2121-2121(1)
Authors: Gibbs B.S.; Coward J.K.