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Publisher: Elsevier

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Volume 13, Number 23, 1 December 2003

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Editorial Board
pp. CO2-CO2(1)

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Contents List
pp. iii

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Graphical Abstracts
pp. 4151-4155(5)

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Semi-synthetic glycopeptide antibacterials
pp. 4165-4168(4)
Authors: Judice, J.K.; Pace, J.L.

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Influence of ethylene-Oxy spacer group on the activity of linezolid: Synthesis of potent antibacterials possessing a thiocarbonyl group
pp. 4169-4172(4)
Authors: Selvakumar, N.; Raheem, M.A.; Khera, M.K.; Rajale, T.V.; Kumar, M.S.; Kandepu, S.; Das, J.; Rajagopalan, R.; Iqbal, J.; Trehan, S.

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Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones
pp. 4173-4177(5)
Authors: Paget, S.D.; Foleno, B.D.; Boggs, C.M.; Goldschmidt, R.M.; Hlasta, D.J.; Weidner-Wells, M.A.; Werblood, H.M.; Wira, E.; Bush, K.; Macielag, M.J.

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New classes of antibacterial oxazolidinones with C-5, methylene O-Linked heterocyclic side chains
pp. 4179-4186(8)
Authors: Gravestock, M.B.; Acton, D.G.; Betts, M.J.; Dennis, M.; Hatter, G.; McGregor, A.; Swain, M.L.; Wilson, R.G.; Woods, L.; Wookey, A.

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Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin
pp. 4187-4191(5)
Authors: Hill, J.; Siedlecki, J.; Parr, I.; Morytko, M.; Yu, X.; Zhang, Y.; Silverman, J.; Controneo, N.; Laganas, V.; Li, T.; Lai, J.; Keith, D.; Shimer, G.; Finn, J.

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The synthesis and antibacterial activity of 1,3,4-Thiadiazole phenyl oxazolidinone analogues
pp. 4193-4196(4)
Authors: Thomasco, L.M.; Gadwood, R.C.; Weaver, E.A.; Ochoada, J.M.; Ford, C.W.; Zurenko, G.E.; Hamel, J.C.; Stapert, D.; Moerman, J.K.; Schaadt, R.D.; Yagi, B.H.

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Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials
pp. 4197-4200(4)
Authors: Johnson, P.D.; Aristoff, P.A.; Zurenko, G.E.; Schaadt, R.D.; Yagi, B.H.; Ford, C.W.; Hamel, J.C.; Stapert, D.; Moerman, J.K.

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MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization
pp. 4201-4204(4)
Authors: Nakayama, K.; Ishida, Y.; Ohtsuka, M.; Kawato, H.; Yoshida, K.; Yokomizo, Y.; Hosono, S.; Ohta, T.; Hoshino, K.; Ishida, H.; Yoshida, K.; Renau, T.E.; Leger, R.; Zhang, J.Z.; Lee, V.J.; Watkins, W.J.

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds
pp. 4205-4208(4)
Authors: Nakayama, K.; Ishida, Y.; Ohtsuka, M.; Kawato, H.; Yoshida, K.; Yokomizo, Y.; Ohta, T.; Hoshino, K.; Otani, T.; Kurosaka, Y.; Yoshida, K.; Ishida, H.; Lee, V.J.; Renau, T.E.; Watkins, W.J.

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New Antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones
pp. 4209-4212(4)
Authors: Singh, U.; Raju, B.; Lam, S.; Zhou, J.; Gadwood, R.C.; Ford, C.W.; Zurenko, G.E.; Schaadt, R.D.; Morin, S.E.; Adams, W.J.; Friis, J.M.; Courtney, M.; Palandra, J.; Hackbarth, C.J.; Lopez, S.; Wu, C.; Mortell, K.H.; Trias, J.; Yuan, Z.; Patel, D.V.; Gordeev, M.F.

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Novel oxazolidinone-quinolone hybrid antimicrobials
pp. 4213-4216(4)
Authors: Gordeev, M.F.; Hackbarth, C.; Barbachyn, M.R.; Banitt, L.S.; Gage, J.R.; Luehr, G.W.; Gomez, M.; Trias, J.; Morin, S.E.; Zurenko, G.E.; Parker, C.N.; Evans, J.M.; White, R.J.; Patel, D.V.

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α-Substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents
pp. 4223-4228(6)
Authors: Jain, R.; Sundram, A.; Lopez, S.; Neckermann, G.; Wu, C.; Hackbarth, C.; Chen, D.; Wang, W.; Ryder, N.S.; Weidmann, B.; Patel, D.; Trias, J.; White, R.; Yuan, Z.

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Structure-activity relationship in the oxazolidinone-quinolone hybrid series: influence of the central spacer on the antibacterial activity and the mode of action
pp. 4229-4233(5)
Authors: Hubschwerlen, C.; Specklin, J.; Baeschlin, D.K.; Borer, Y.; Haefeli, S.; Sigwalt, C.; Schroeder, S.; Locher, H.H.

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The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones
pp. 4235-4239(5)
Authors: Ciske, F.L.; Barbachyn, M.R.; Genin, M.J.; Grega, K.C.; Lee, C.S.; Dolak, L.A.; Seest, E.P.; Watt, W.; Adams, W.J.; Friis, J.M.; Ford, C.W.; Zurenko, G.E.

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The relationship between physicochemical properties, In vitro activity and pharmacokinetic profiles of analogues of diamine-Containing efflux pump inhibitors
pp. 4241-4244(4)
Authors: Watkins, W.J.; Landaverry, Y.; Leger, R.; Litman, R.; Renau, T.E.; Williams, N.; Yen, R.; Zhang, J.Z.; Chamberland, S.; Madsen, D.; Griffith, D.; Tembe, V.; Huie, K.; Dudley, M.N.

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Array synthesis of novel lipodepsipeptide
pp. 4245-4249(5)
Authors: Siedlecki, J.; Hill, J.; Parr, I.; Yu, X.; Morytko, M.; Zhang, Y.; Silverman, J.; Controneo, N.; Laganas, V.; Li, T.; Li, J.; Keith, D.; Shimer, G.; Finn, J.

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