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Publisher: Elsevier

Volume 13, Number 9, 5 May 2003

Editorial board
pp. CO2-CO2(1)

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Contents List
pp. iii-iv(2)

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Graphical Abstracts
pp. 1499-1504(6)

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Synthesis, in vitro, and in vivo evaluation of phosphate ester derivatives of combretastatin A-4
pp. 1505-1508(4)
Authors: Hadimani, M.B.; Hua, J.; Jonklaas, M.D.; Kessler, R.J.; Sheng, Y.; Olivares, A.; Tanpure, R.P.; Weiser, A.; Zhang, J.; Edvardsen, K.; Kane, R.R.; Pinney, K.G.

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Effects of 8-chlorodeoxyadenosine on DNA synthesis by the klenow fragment of DNA polymerase I
pp. 1509-1512(4)
Authors: Chen, L.S.; Bahr, M.H.; Sheppard, T.L.

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Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo
pp. 1513-1515(3)
Authors: Zobel, K.; Koehler, M.F.T.; Beresini, M.H.; Caris, L.D.; Combs, D.

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor  (PPAR)-synthesis and biological activity
pp. 1517-1521(5)
Authors: Sznaidman, M.L.; Haffner, C.D.; Maloney, P.R.; Fivush, A.; Chao, E.; Goreham, D.; Sierra, M.L.; LeGrumelec, C.; Xu, H.E.; Montana, V.G.; Lambert, M.H.; Willson, T.M.; Oliver, W.R.; Sternbach, D.D.

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A novel metal-Chelating inhibitor of protein farnesyltransferase
pp. 1523-1526(4)
Authors: Hamasaki, A.; Naka, H.; Tamanoi, F.; Umezawa, K.; Otsuka, M.

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Synthesis and collateral dilator activity of nitroxyalkylamides having direct or latent sulfhydryl moieties
pp. 1527-1530(4)
Authors: Ishihara, S.; Saito, F.; Ohhata, Y.; Kanai, M.; Mizuno, H.; Fujisawa, M.; Yorikane, R.; Koike, H.

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Structure-Activity relationships of novel anti-malarial agents. Part 6: N-(4-Arylpropionylamino-3-benzoylphenyl)-[5-(4-nitrophenyl)-2-furyl]acrylic acid amides
pp. 1539-1541(3)
Authors: Wiesner, J.; Fucik, K.; Kettler, K.; Sakowski, J.; Ortmann, R.; Jomaa, H.; Schlitzer, M.

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5-Imidazolyl-quinolinones, -quinazolinones and -benzo-azepinones as farnesyltransferase inhibitors
pp. 1543-1547(5)
Authors: Angibaud, P.; Bourdrez, X.; Devine, A.; End, D.W.; Freyne, E.; Ligny, Y.; Muller, P.; Mannens, G.; Pilatte, I.; Poncelet, V.; Skrzat, S.; Smets, G.; van Dun, J.; van Remoortere, P.; Venet, M.; Wouters, W.

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Chain-Branched acyclic phenethylthiocarbamates as vanilloid receptor antagonists
pp. 1549-1552(4)
Authors: Yoon, J.; Choi, H.; Lee, H.J.; Ryu, C.H.; Park, H.; Suh, Y.; Oh, U.; Jeong, Y.S.; Choi, J.K.; Park, Y.; Kim H.-D.

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Preparation and pharmacological profile of 7-(α-Azolylbenzyl)-1H-indoles and indolines as new aromatase inhibitors
pp. 1553-1555(3)
Authors: Marchand, P.; Le Borgne, M.; Palzer, M.; Le Baut, G.; Hartmann, R.W.

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Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme mur D
pp. 1557-1560(4)
Authors: Horton, J.R.; Bostock, J.M.; Chopra, I.; Hesse, L.; Phillips, S.E.V.; Adams, D.J.; Johnson, A.P.; Fishwick, C.W.G.

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Nonpeptide RGD antagonists: A novel class of mimetics, the 5,8-disubstituted 1-azabicyclo[5.2.0]nonan-2-one lactam
pp. 1561-1564(4)
Authors: Bourguet, E.; Baneres, J.; Parello, J.; Lusinchi, X.; Girard J.-P.; Vidal, J.

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Controlling the intracellular localization of fluorescent polyamide analogues in cultured cells
pp. 1565-1570(6)
Authors: Crowley, K.S.; Phillion, D.P.; Woodard, S.S.; Schweitzer, B.A.; Singh, M.; Shabany, H.; Burnette, B.; Hippenmeyer, P.; Heitmeier, M.; Bashkin, J.K.

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Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability
pp. 1571-1574(4)
Authors: Tong, Y.; Lin, N.; Wang, L.; Hasvold, L.; Wang, W.; Leonard, N.; Li, T.; Li, Q.; Cohen, J.; Gu, W.; Zhang, H.; Stoll, V.; Bauch, J.; Marsh, K.; Rosenberg, S.H.; Sham, H.L.

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Anti-HIV Agents. Part 55: 3'R,4'R-Di-(O)-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP), a Novel Anti-HIV agent
pp. 1575-1576(2)
Authors: Yu, D.; Brossi, A.; Kilgore, N.; Wild, C.; Allaway, G.; Lee K.-H.

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5-Aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)
pp. 1577-1580(4)
Authors: Witherington, J.; Bordas, V.; Garland, S.L.; Hickey, D.M.B.; Ife, R.J.; Liddle, J.; Saunders, M.; Smith, D.G.; Ward, R.W.

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5-Aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)
pp. 1581-1584(4)
Authors: Witherington, J.; Bordas, V.; Haigh, D.; Hickey, D.M.B.; Ife, R.J.; Rawlings, A.D.; Slingsby, B.P.; Smith, D.G.; Ward, R.W.

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New scaffolds in the development of Mu opioid-receptor ligands
pp. 1585-1589(5)
Authors: Page, D.; Nguyen, N.; Bernard, S.; Coupal, M.; Gosselin, M.; Lepage, J.; Adam, L.; Brown, W.

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The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity
pp. 1597-1600(4)
Authors: Liu, W.; Sheppeck, J.E.; Colby, D.A.; Huang, H.; Nairn, A.C.; Chamberlin, A.R.

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A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure
pp. 1601-1605(5)
Authors: Colby, D.A.; Liu, W.; Sheppeck, J.E.; Huang, H.; Nairn, A.C.; Chamberlin, A.R.

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