Bioorganic and Medicinal Chemistry Letters

Editorial Board
pp. CO2-CO2(1)

Contents List
pp. iii

Contributors to this Issue
pp. vii

Graphical Abstracts
pp. 771-781(11)

Peptidyl aldehyde inhibitors of calpain incorporating P₂-proline mimetics
pp. 783-784(2)
Authors: Donkor I.O.; Korukonda R.; Huang T.L.; LeCour L.

Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors
pp. 785-788(4)
Authors: Glunz P.W.; Douty B.D.; Decicco C.P.

Novel thrombin inhibitors incorporating non-basic partially saturated heterobicyclic P₁-Arginine mimetics
pp. 789-794(6)
Authors: Peterlin-Masic L.; Mlinsek G.; Solmajer T.; Trampus-Bakija A.; Stegnar M.; Kikelj D.

Azaindoles: moderately basic P1 groups for enhancing the selectivity of thrombin inhibitors
pp. 795-798(4)
Authors: Sanderson P.E.J.; Stanton M.G.; Dorsey B.D.; Lyle T.A.; McDonough C.; Sanders W.M.; Savage K.L.; Naylor-Olsen A.M.; Krueger J.A.; Lewis S.D.; Lucas B.J.; Lynch J.J.; Yan Y.

An adjustable release rate linking strategy for cytotoxin-Peptide conjugates
pp. 799-803(5)
Authors: Fuselier J.A.; Sun L.; Woltering S.N.; Murphy W.A.; Vasilevich N.; Coy D.H.

Dehydrophenylalanine derivatives as VLA-4 integrin antagonists
pp. 805-808(4)
Authors: Porter J.R.; Archibald S.C.; Brown J.A.; Childs K.; Critchley D.; Head J.C.; Parton T.A.H.; Robinson M.K.; Shock A.; Taylor R.J.; Warrellow G.J.

Novel synthesis of 2-Substituted 19-norvitamin D A-ring phosphine oxide from d-glucose as a building block
pp. 809-812(4)
Authors: Shimizu M.; Iwasaki Y.; Shibamoto Y.; Sato M.; DeLuca H.F.; Yamada S.

Design, synthesis, and evaluation of -galactosylceramide mimics promoting -glucocerebrosidase activity in keratinocytes
pp. 813-815(3)
Authors: Fukunaga K.; Yoshida M.; Nakajima F.; Uematsu R.; Hara M.; Inoue S.; Kondo H.; Nishimura S.-I.

Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A₃ receptor ligands
pp. 817-820(4)
Authors: Lim M.H.; Kim H.O.; Moon H.R.; Lee S.J.; Chun M.W.; Gao Z.-G.; Melman N.; Jacobson K.A.; Kim J.H.; Jeong L.S.

Antiplatelet activity of synthetic pyrrolo-benzylisoquinolines
pp. 821-823(3)
Authors: Kuo R.-Y.; Wu C.-C.; Chang F.-R.; Yeh J.-L.; Chen I.-J.; Wu Y.-C.

Interaction of binuclear xylylthiolato(2,2',2''-terpyridine)platinum(II) complexes with DNA
pp. 825-828(4)
Authors: Kurosaki H.; Yamakawa N.; Sumimoto M.; Kimura K.; Goto M.

2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists
pp. 829-832(4)
Authors: Buttelmann B.; Alanine A.; Bourson A.; Gill R.; Heitz M.-P.; Mutel V.; Pinard E.; Trube G.; Wyler R.

Hydroporphyrins as tumour photosensitizers: synthesis and photophysical studies of 2,3-Dihydro-5,15-di(3,5-dihydroxyphenyl) porphyrin
pp. 833-835(3)
Authors: Ferrand Y.; Bourre L.; Simonneaux G.; Thibaut S.; Odobel F.; Lajat Y.; Patrice T.

Carbonic anhydrase inhibitors - inhibition of cytosolic isozymes I and II with sulfamide derivatives
pp. 837-840(4)
Authors: Casini A.; Winum J.-Y.; Montero J.-L.; Scozzafava A.; Supuran C.T.

Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV
pp. 841-845(5)
Authors: Casini A.; Antel J.; Abbate F.; Scozzafava A.; David S.; Waldeck H.; Schafer S.; Supuran C.T.

Oligonucleotides containing a new type of acyclic, achiral nucleoside analogue: 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine
pp. 847-850(4)
Authors: Boesen T.; Pedersen D.S.; Nielsen B.M.; Petersen A.B.; Henriksen U.; Dahl B.M.; Dahl O.

Cyclic Amidines as Benzamide Bioisosteres: EPC Synthesis and SAR Studies Leading to the Selective Dopamine D4 Receptor Agonist FAUC 312
pp. 851-854(4)
Authors: Einsiedel J.; Hubner H.; Gmeiner P.

Bis(acridinylthiourea)platinum(II) complexes: synthesis, DNA affinity, and biological activity in glioblastoma cells
pp. 855-858(4)
Authors: Augustus T.M.; Anderson J.; Hess S.M.; Bierbach U.

Synthesis of a new family of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders
pp. 859-862(4)
Authors: Durand G.; Polidori A.; Salles J.-P.; Pucci B.

Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II
pp. 863-865(3)
Authors: Vicker N.; Ho Y.; Robinson J.; Woo L.L.W.; Purohit A.; Reed M.J.; Potter B.V.L.

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine
pp. 867-872(6)
Authors: Hattori K.; Kohchi Y.; Oikawa N.; Suda H.; Ura M.; Ishikawa T.; Miwa M.; Endoh M.; Eda H.; Tanimura H.; Kawashima A.; Horii I.; Ishitsuka H.; Shimma N.

Discovery of the first antibacterial small molecule inhibitors of MurB
pp. 873-875(3)
Authors: Bronson J.J.; DenBleyker K.L.; Falk P.J.; Mate R.A.; Ho H.-T.; Pucci M.J.; Snyder L.B.

Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
pp. 877-880(4)
Authors: Brathe A.; Gundersen L.-L.; Nissen-Meyer J.; Rise F.; Spilsberg B.

Synthesis and anticancer effect of chrysin derivatives
pp. 881-884(4)
Authors: Zheng X.; Meng W.-D.; Xu Y.-Y.; Cao J.-G.; Qing F.-L.

N-(3-Phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonists
pp. 885-890(6)
Authors: Gutteridge C.E.; de Laszlo S.E.; Kamenecka T.M.; McCauley E.; van Riper G.; Mumford R.A.; Kidambi U.; Egger L.A.; Tong S.; Hagmann W.K.

Substituted quinolines induce inhibition of proliferation of HTLV-1 infected cells
pp. 891-894(4)
Authors: Fournet A.; Mahieux R.; Fakhfakh M.A.; Franck X.; Hocquemiller R.; Figadere B.

Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain
pp. 895-899(5)
Authors: Li P.; Peach M.L.; Zhang M.; Liu H.; Yang D.; Nicklaus M.; Roller P.P.

Synthesis of (+),(-)-neamine and their positional isomers as potential antibiotics
pp. 901-903(3)
Authors: Ryu D.H.; Tan C.-H.; Rando R.R.

Design, synthesis and photochemical properties of caged bile acids
pp. 905-908(4)
Authors: Hirayama Y.; Iwamura M.; Furuta T.

Why B-ring is the active center for genistein to scavenge peroxyl radical: A DFT study
pp. 909-911(3)
Authors: Zhang H.-Y.; Wang L.-F.; Sun Y.-M.

Discovery of novel and selective IKK- serine-threonine protein kinase inhibitors. Part 1
pp. 913-918(6)
Authors: Murata T.; Shimada M.; Sakakibara S.; Yoshino T.; Kadono H.; Masuda T.; Shimazaki M.; Shintani T.; Fuchikami K.; Sakai K.; Inbe H.; Takeshita K.; Niki T.; Umeda M.; Bacon K.B.; Ziegelbauer K.B.; Lowinger T.B.

Discovery of novel neuronal voltage-Dependent calcium channel blockers based on emopamil left hand as a bioactive template
pp. 919-922(4)
Authors: Suzuki Y.; Yamamoto N.; Iimura Y.; Kawano K.; Kimura T.; Nagato S.; Ito K.; Komatsu M.; Norimine Y.; Kimura M.; Teramoto T.; Kaneda Y.; Hamano T.; Niidome T.; Yonaga M.

Plasmid relaxation induced by copper metalated diglycine conjugates under heterogeneous reaction conditions
pp. 923-926(4)
Authors: Madhavaiah C.; Verma S.

Acylcyclohexanedione derivatives as potential in vivo sequential inhibitors of 4-hydroxyphenylpyruvate dioxygenase and GA₂₀ 3-hydroxylase
pp. 927-930(4)
Authors: Huang J.-L.; Liu H.-G.; Yang D.-Y.

Amphipathic 3-Phenyl-7-propylbenzisoxazoles; human pPaR , and agonists
pp. 931-935(5)
Authors: Adams A.D.; Yuen W.; Hu Z.; Santini C.; Jones A.B.; MacNaul K.L.; Berger J.P.; Doebber T.W.; Moller D.E.

Total synthesis and adjuvant activity of all stereoisomers of pinellic acid
pp. 937-941(5)
Authors: Shirahata T.; Sunazuka T.; Yoshida K.; Yamamoto D.; Harigaya Y.; Nagai T.; Kiyohara H.; Yamada H.; Kuwajima I.; Omura S.

Highly cytotoxic benzo[c]pyrido[2,3,4-kl]acridines
pp. 943-946(4)
Authors: Chackal S.; Facompre M.; Houssin R.; Goossens J.-F.; Pommery N.; Henichart J.-P.; Bailly C.

Cancer chemotherapy: A SN-38 (7-Ethyl-10-hydroxycamptothecin) glucuronide prodrug for treatment by a PMT (Prodrug monoTherapy) strategy
pp. 947-950(4)
Authors: Angenault S.; Thirot S.; Schmidt F.; Monneret C.; Pfeiffer B.; Renard P.

Bis-sulfonamides as endothelin receptor antagonists
pp. 951-954(4)
Authors: Boss C.; Bolli M.H.; Weller T.; Fischli W.; Clozel M.

The use of sulfonylamido pyrimidines incorporating an unsaturated side chain as endothelin receptor antagonists
pp. 955-959(5)
Authors: Bolli M.H.; Boss C.; Clozel M.; Fischli W.; Hess P.; Weller T.

Synthesis and thrombolytic activity of fibrinogen fragment related cyclopeptides
pp. 961-964(4)
Authors: Zhao M.; Lin N.; Wang C.; Peng S.

Synthesis and photoreactivity of caged blockers for glutamate transporters
pp. 965-970(6)
Authors: Takaoka K.; Tatsu Y.; Yumoto N.; Nakajima T.; Shimamoto K.

Modification of the N-terminus of peptidomimetic protein tyrosine phosphatase 1B (PTP1B) inhibitors: identification of analogues with cellular activity
pp. 971-975(5)
Authors: Larsen S.D.; Stevens F.C.; Lindberg T.J.; Bodnar P.M.; O'Sullivan T.J.; Schostarez H.J.; Palazuk B.J.; Bleasdale J.E.

Erratum to 'Structure-Activity and Crystallographic Analysis of Benzophenone Derivatives-the Potential Anticancer Agents' [Bioorg. Med. Chem. Lett. 13 (2003) 101]^&unknown;
pp. 977-977(1)
Authors: Hsieh H.-P.; Liou J.-P.; Lin Y.-T.; Mahindroo N.; Chang J.-Y.; Yang Y.-N.; Chern S.-S.; Tan U.-K.; Chang C.-W.; Chen T.-W.; Lin C.-H.; Chang Y.-Y.; Wang C.-C.