Bioorganic and Medicinal Chemistry Letters

Inside (Editorial Board)
pp. CO2-CO2(1)

Contents List
pp. iii-v(3)

Contributors to this Issue
pp. vii-viii(2)

Author Index 2002
pp. IX-XXXIX(31)

Volume Contents 2002
pp. XLI-XCV(55)

Graphical Abstracts
pp. 3497-3504(8)

Synthesis and cytotoxic activity of a new potent daunomycinone derivative
pp. 3505-3507(3)
Authors: Aligiannis N.; Pouli N.; Marakos P.; Skaltsounis A.-L.; Pratsinis H.

Bioactive 4-substituted-6-methyl-2-pyrones with promising cytotoxicity against A2780 and K562 cell lines
pp. 3509-3513(5)
Authors: Marrison L.R.; Dickinson J.M.; Fairlamb I.J.S.

A novel synthesis of d-galactofuranosyl, d-glucofuranosyl and d-mannofuranosyl 1-phosphates based on remote activation of new and free hexofuranosyl donors
pp. 3515-3518(4)
Authors: Ferrieres V.; Blanchard S.; Fischer D.; Plusquellec D.

Synthesis of (+)-Lasonolide A: (-)-Lasonolide A is the biologically active enantiomer
pp. 3519-3520(2)
Authors: Lee E.; Song H.Y.; Joo J.M.; Kang J.W.; Kim D.S.; Jung C.K.; Hong C.Y.; Jeong S.; Jeon K.

Stereoselective and improved syntheses and anticancer testing of 3'-O-silatranylthymidines
pp. 3521-3523(3)
Authors: Black C.A.; Ucci J.W.; Vorpagel J.S.; Mauck M.C.; Fenlon E.E.

Vacuolar-type H⁺-ATPase inhibitory activity of synthetic analogues of the concanamycins: Is the hydrogen bond network involving the lactone carbonyl, the hemiacetal hydroxy group, and the C-19 hydroxy group essential for the biological activity of the concanamycins?
pp. 3525-3528(4)
Authors: Yoshimoto Y.; Jyojima T.; Arita T.; Ueda M.; Imoto M.; Matsumura S.; Toshima K.

Synthesis of new targretin(R) analogues that induce apoptosis in leukemia HL-60 cells
pp. 3529-3532(4)
Authors: Winum J.-Y.; Baghdiguian S.; Commes T.; Leydet A.; Montero J.-L.

Design and efficient synthesis of new stable 1,25-dihydroxy-19-norvitamin D₃ analogues containing amide bond
pp. 3533-3536(4)
Authors: Suhara Y.; Kittaka A.; Ono K.; Kurihara M.; Fujishima T.; Yoshida A.; Takayama H.

Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics
pp. 3537-3541(5)
Authors: Fraley M.E.; Rubino R.S.; Hoffman W.F.; Hambaugh S.R.; Arrington K.L.; Hungate R.W.; Bilodeau M.T.; Tebben A.J.; Rutledge R.Z.; Kendall R.L.; McFall R.C.; Huckle W.R.; Coll K.E.; Thomas K.A.

Synthesis of aglycon analogues of sarmentosin and Their bioactivity of lymphocyte proliferation
pp. 3543-3545(3)
Authors: Zhang H.; Xu R.; Hu Z.; He X.; Bai D.; Li X.; Wang X.

Nitrite-Mediated decarboxylative conjugation of caffeic acid with glutathione under mildly acidic conditions
pp. 3547-3550(4)
Authors: Panzella L.; Napolitano A.; d'Ischia M.

Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. synthesis and SAR studies
pp. 3551-3555(5)
Authors: Carotti A.; Carrieri A.; Chimichi S.; Boccalini M.; Cosimelli B.; Gnerre C.; Carotti A.; Carrupt P.-A.; Testa B.

Synthesis and biological evaluation of aristolactams
pp. 3557-3559(3)
Authors: Couture A.; Deniau E.; Grandclaudon P.; Rybalko-Rosen H.; Leonce S.; Pfeiffer B.; Renard P.

Synthesis and biological evaluation of novel 2-(1H-imidazol-4-yl)cyclopropane carboxylic acids: key intermediates for H₃ histamine receptor ligands
pp. 3561-3563(3)
Authors: Brana M.F.; Guisado C.; Fernando Alguacil L.; Garrido E.; Perez-Garca C.; Ruiz-Gayo M.

Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators
pp. 3565-3567(3)
Authors: Thor M.; Beierlein K.; Dykes G.; Gustavsson A.-L.; Heidrich J.; Jendeberg L.; Lindqvist B.; Pegurier C.; Roussel P.; Slater M.; Svensson S.; Sydow-Backman M.; Thornstrom U.; Uppenberg J.

17S,20S-Methanofusidic acid, a new potent semi-synthetic fusidane antibiotic
pp. 3569-3572(4)
Authors: Duvold T.; Jorgensen A.; Andersen N.R.; Henriksen A.S.; Dahl Sorensen M.; Bjorkling F.

2-(Dimethylaminomethyl)-tetrahydroisoxazolopyridobenzazepine derivatives. Synthesis of a new 5-HT_2C antagonist with potential anxiolytic properties
pp. 3573-3577(5)
Authors: Andres J.I.; Alonso J.M.; Fernandez J.; Iturrino L.; Martnez P.; Meert T.F.; Sipido V.K.

Synthetic studies of cis-4-Amino-l-proline derivatives as novel lipid lowering agents
pp. 3579-3581(3)
Authors: Das S.K.; Narasimha Rao Krovvidi V.L.; Jagadheshan H.; Iqbal J.

Novel 1',1'-chain substituted ⁸-tetrahydrocannabinols
pp. 3583-3586(4)
Authors: Papahatjis D.P.; Nikas S.P.; Andreou T.; Makriyannis A.

Isolation and antimalarial activity of peroxydisulfate oxidation products of primaquine
pp. 3587-3589(3)
Authors: Dua V.K.; Sinha S.N.; Biswas S.; Valecha N.; Puri S.K.; Sharma V.P.

Reductively activated disulfide prodrugs of paclitaxel
pp. 3591-3594(4)
Authors: Vrudhula V.M.; MacMaster J.F.; Li Z.; Kerr D.E.; Senter P.D.

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group
pp. 3595-3599(5)
Authors: Smith H.K.; Beckett R.P.; Clements J.M.; Doel S.; East S.P.; Launchbury S.B.; Pratt L.M.; Spavold Z.M.; Thomas W.; Todd R.S.; Whittaker M.

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides
pp. 3601-3604(4)
Authors: Millet R.; Maes L.; Landry V.; Sergheraert C.; Davioud-Charvet E.

A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results
pp. 3605-3609(5)
Authors: Demetzos C.; Kolocouris A.; Anastasaki T.

Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter
pp. 3611-3613(3)
Authors: Sandell J.; Yu M.; Emond P.; Garreau L.; Chalon S.; Nagren K.; Guilloteau D.; Halldin C.

An expedient synthesis of N-protected-l-tetrahydrofuranylglycine and its application in the synthesis of novel substrate based inhibitors of HIV-1 protease
pp. 3615-3617(3)
Authors: Rajesh S.; Ami E.; Kotake T.; Kimura T.; Hayashi Y.; Kiso Y.

Scanning the prime-Site substrate specificity of proteolytic enzymes: A novel assay based on ligand-Enhanced lanthanide ion fluorescence
pp. 3619-3623(5)
Authors: Barrios A.M.; Craik C.S.

Silanediol-Based inhibitor of thermolysin
pp. 3625-3627(3)
Authors: Kim J.; Glekas A.; Sieburth S.M.

Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives
pp. 3629-3633(5)
Authors: Manna F.; Chimenti F.; Bolasco A.; Secci D.; Bizzarri B.; Befani O.; Turini P.; Mondov B.; Alcaro S.; Tafi A.

Characterization of mono- and diaminopyrimidine derivatives as novel, nonpeptide gonadotropin releasing hormone (GnRH) receptor antagonists
pp. 3635-3639(5)
Authors: Luthin D.R.; Hong Y.; Tompkins E.; Anderes K.L.; Paderes G.; Kraynov E.A.; Castro M.A.; Nared-Hood K.D.; Castillo R.; Gregory M.; Vazir H.; May J.M.; Anderson M.B.

Unique hole-Trapping property of the degenerate base,2-amino-7-deazaadenine
pp. 3641-3643(3)
Authors: Okamoto A.; Tanaka K.; Saito I.

Erratum to ''Tryptophanyl phosphoramidates as prodrugs of synadenol and its E-isomer: synthesis and biological activity'' [Bioorg. Med. Chem. Lett. 12 (2002) 2467]
pp. 3645-3645(1)
Authors: Wang R.; Corbett T.H.; Cheng Y.-C.; Drach J.C.; Kern E.R.; Mitsuya H.; Zemlicka J.