If you are experiencing problems downloading PDF or HTML fulltext, our helpdesk recommend clearing your browser cache and trying again. If you need help in clearing your cache, please click here . Still need help? Email help@ingentaconnect.com

Publisher: Elsevier

Related content
Volume 12, Number 21, 4 November 2002

< previous issue | all issues | next issue >

Favourites:Add to Favourites

Contents List
pp. iii

Favourites:Add to Favourites
Favourites:Add to Favourites

Graphical Abstracts
pp. 3015-3026(12)

Favourites:Add to Favourites
Favourites:Add to Favourites
Favourites:Add to Favourites

Structure-Activity relationships of 2-substituted 5,7-Diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acids as a novel class of endothelin receptor antagonists
pp. 3041-3045(5)
Authors: Niiyama, K.; Takahashi, H.; Nagase, T.; Kojima, H.; Amano, Y.; Katsuki, K.; Yamakawa, T.; Ozaki, S.; Ihara, M.; Yano, M.; Fukuroda, T.; Nishikibe, M.; Ishikawa, K.

Favourites:Add to Favourites

α-Bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship
pp. 3047-3050(4)
Authors: Arabaci, G.; Yi, T.; Fu, H.; Porter, M.E.; Beebe, K.D.; Pei, D.

Favourites:Add to Favourites

A series of C-Terminal amino alcohol dipeptide A inhibitors
pp. 3051-3053(3)
Authors: Garofalo, A.W.; Wone, D.W.G.; Phuc, A.; Audia, J.E.; Bales, C.A.; Dovey, H.F.; Dressen, D.B.; Folmer, B.; Goldbach, E.G.; Guinn, A.C.; Latimer, L.H.; Mabry, T.E.; Nissen, J.S.; Pleiss, M.A.; Sohn, S.; Thorsett, E.D.; Tung, J.S.; Wu, J.

Favourites:Add to Favourites

Synthesis and evaluation of potent pyrrolidine H3 antagonists
pp. 3055-3058(4)
Authors: Vasudevan, A.; Conner, S.E.; Gentles, R.G.; Faghih, R.; Liu, H.; Dwight, W.; Ireland, L.; Kang, C.H.; Esbenshade, T.A.; Bennani, Y.L.; Hancock, A.A.

Favourites:Add to Favourites

Synthesis and biological activity of potent heterocyclic thiol-based inhibitors of endothelin-converting enzyme-1
pp. 3059-3062(4)
Authors: Firooznia, F.; Gude, C.; Chan, K.; Tan, J.; Fink, C.A.; Savage, P.; Beil, M.E.; Bruseo, C.W.; Trapani, A.J.; Jeng, A.Y.

Favourites:Add to Favourites

Novel nucleotide phosphonate analogues with potent antitumor activity
pp. 3063-3066(4)
Authors: Bubenik, M.; Rej, R.; Nguyen-Ba, N.; Attardo, G.; Ouellet, F.; Chan, L.

Favourites:Add to Favourites

bis-Azaaromatic quaternary ammonium analogues: ligands for α42* and α7* subtypes of neuronal nicotinic receptors
pp. 3067-3071(5)
Authors: Ayers, J.T.; Dwoskin, L.P.; Deaciuc, A.G.; Grinevich, V.P.; Zhu, J.; Crooks, P.A.

Favourites:Add to Favourites

Parallel solution- and solid-phase synthesis of spiropyrrolo-Pyrroles as novel neurokinin receptor ligands
pp. 3073-3076(4)
Authors: Bleicher, K.H.; Wuthrich, Y.; Adam, G.; Hoffmann, T.; Sleight, A.J.

Favourites:Add to Favourites

Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands
pp. 3077-3079(3)
Authors: Faghih, R.; Dwight, W.; Vasudevan, A.; Dinges, J.; Conner, S.E.; Esbenshade, T.A.; Bennani, Y.L.; Hancock, A.A.

Favourites:Add to Favourites

Bridged bicyclic vasopressin receptor antagonists with V2-Selective or dual V1a/V2 activity
pp. 3081-3084(4)
Authors: Dyatkin, A.B.; Hoekstra, W.J.; Hlasta, D.; Andrade-Gordon, P.; de Garavilla, L.; Demarest, K.T.; Gunnet, J.W.; Hageman, W.; Look, R.; Maryanoff, B.E.

Favourites:Add to Favourites

Hydroxamate based inhibitors of adenylyl cyclase. Part 1: The effect of acyclic linkers on P-site binding
pp. 3085-3088(4)
Authors: Levy, D.E.; Marlowe, C.; Kane-Maguire, K.; Bao, M.; Cherbavaz, D.B.; Tomlinson, J.E.; Sedlock, D.M.; Scarborough, R.M.

Favourites:Add to Favourites

Hydroxamate based inhibitors of adenylyl cyclase. Part 2: The effect of cyclic linkers on P-site binding
pp. 3089-3092(4)
Authors: Levy, D.E.; Bao, M.; Tomlinson, J.E.; Scarborough, R.M.

Favourites:Add to Favourites

A general synthesis of specifically deuterated nucleotides for studies of DNA and RNA
pp. 3093-3096(4)
Authors: Chen, B.; Jamieson, E.R.; Tullius, T.D.

Favourites:Add to Favourites

Synthesis and evaluation of 5-HT2A and 5-HT2C receptor binding affinities of novel pyrimidine derivatives
pp. 3097-3099(3)
Authors: Bozsing, D.; Simonek, I.; Simig, G.; Jakoczi, I.; Gacsalyi, I.; Levay, G.; Tihanyi, K.; Schmidt, E.

Favourites:Add to Favourites

Novel lopinavir analogues incorporating non-Aromatic P-1 side chains-Synthesis and structure-Activity relationships
pp. 3101-3103(3)
Authors: Sham, H.L.; Zhao, C.; Li, L.; Betebenner, D.A.; Saldivar, A.; Vasavanonda, S.; Kempf, D.J.; Plattner, J.J.; Norbeck, D.W.

Favourites:Add to Favourites

Indoline and piperazine containing derivatives as a novel class of mixed D2/D4 receptor antagonists. Part 1: Identification and structure-activity relationships
pp. 3105-3109(5)
Authors: Zhao, H.; Thurkauf, A.; He, X.; Hodgetts, K.; Zhang, X.; Rachwal, S.; Kover, R.X.; Hutchison, A.; Peterson, J.; Kieltyka, A.; Brodbeck, R.; Primus, R.; Wasley, J.W.F.

Favourites:Add to Favourites

Indoline and piperazine containing derivatives as a novel class of mixed D2/D4 receptor antagonists. Part 2: Asymmetric synthesis and biological evaluation
pp. 3111-3115(5)
Authors: Zhao, H.; He, X.; Thurkauf, A.; Hoffman, D.; Kieltyka, A.; Brodbeck, R.; Primus, R.; Wasley, J.W.F.

Favourites:Add to Favourites

Inhibition of HIV-1 nuclear import via schiff base formation with arylene bis(methylketone) compounds
pp. 3117-3119(3)
Authors: Al-Abed, Y.; Dubrovsky, L.; Ruzsicska, B.; Seepersaud, M.; Bukrinsky, M.

Favourites:Add to Favourites
Favourites:Add to Favourites

A survey of cyclic replacements for the central diamide moiety of inhibitors of inosine monophosphate dehydrogenase
pp. 3125-3128(4)
Authors: Dhar, T.G.M.; Liu, C.; Pitts, W.J.; Guo, J.; Watterson, S.H.; Gu, H.; Fleener, C.A.; Rouleau, K.; Sherbina, N.Z.; Barrish, J.C.; Hollenbaugh, D.; Iwanowicz, E.J.

Favourites:Add to Favourites

Highly potent non-peptidic inhibitors of the HCV NS3/NS4A serine protease
pp. 3129-3133(5)
Authors: Sperandio, D.; Gangloff, A.R.; Litvak, J.; Goldsmith, R.; Hataye, J.M.; Wang, V.R.; Shelton, E.J.; Elrod, K.; Janc, J.W.; Clark, J.M.; Rice, K.; Weinheimer, S.; Yeung, K.; Meanwell, N.A.; Hernandez, D.; Staab, A.J.; Venables, B.L.; Spencer, J.R.

Favourites:Add to Favourites

DNA Interaction and photonicking properties of DNA-Targeted acridine (2,2'-Bipyridine)Platinum(II) complexes
pp. 3135-3139(5)
Authors: Gude, L.; Fernandez, M.; Grant, K.B.; Lorente, A.

Favourites:Add to Favourites

Synthesis and structure-activity relationship of novel aminotetralin derivatives with high  selective opioid affinity
pp. 3141-3143(3)
Authors: Roy, C.; Li, T.; Krasik, P.; Gilbert, M.; Pelletier, C.; Gagnon, D.; Robert, E.; Ducharme, J.; Storer, R.; Lavallee, J.

Favourites:Add to Favourites

Synthesis and biological activity of retinoic acid receptor-α specific amides
pp. 3145-3148(4)
Authors: Beard, R.L.; Duong, T.T.; Teng, M.; Klein, E.S.; Standevan, A.M.; Chandraratna, R.A.S.

Favourites:Add to Favourites

Design and synthesis of xanthine analogues as potent and selective PDE5 inhibitors
pp. 3149-3152(4)
Authors: Wang, Y.; Chackalamannil, S.; Hu, Z.; Boyle, C.D.; Lankin, C.M.; Xia, Y.; Xu, R.; Asberom, T.; Pissarnitski, D.; Stamford, A.W.; Greenlee, W.J.; Skell, J.; Kurowski, S.; Vemulapalli, S.; Palamanda, J.; Chintala, M.; Wu, P.; Myers, J.; Wang, P.

Favourites:Add to Favourites

Synthesis and SAR of novel imidazoquinoxaline-Based Lck inhibitors: improvement of cell potency
pp. 3153-3156(4)
Authors: Chen, P.; Iwanowicz, E.J.; Norris, D.; Gu, H.H.; Lin, J.; Moquin, R.V.; Das, J.; Wityak, J.; Spergel, S.H.; de Fex, H.; Pang, S.; Pitt, S.; Shen, D.R.; Schieven, G.L.; Barrish, J.C.

Favourites:Add to Favourites

Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands
pp. 3157-3160(4)
Authors: Wu, W.; Caplen, M.A.; Domalski, M.S.; Zhang, H.; Fawzi, A.; Burnett, D.A.

Favourites:Add to Favourites

Synthesis and NK1/NK2 binding activities of a series of diacyl-substituted 2-arylpiperazines
pp. 3161-3165(5)
Authors: Blythin, D.J.; Chen, X.; Piwinski, J.J.; Shih, N.; Shue, H.; Anthes, J.C.; McPhail, A.T.

Favourites:Add to Favourites

A mechanism-based probe for gp120-Hydrolyzing antibodies
pp. 3167-3170(4)
Authors: Taguchi, H.; Burr, G.; Karle, S.; Planque, S.; Zhou, Y.; Paul, S.; Nishiyama, Y.

Favourites:Add to Favourites

The antimicrobial natural product chuangxinmycin and Some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase
pp. 3171-3174(4)
Authors: Brown, M.J.; Carter, P.S.; Fenwick, A.E.; Fosberry, A.P.; Hamprecht, D.W.; Hibbs, M.J.; Jarvest, R.L.; Mensah, L.; Milner, P.H.; O'Hanlon, P.J.; Pope, A.J.; Richardson, C.M.; West, A.; Witty, D.R.

Favourites:Add to Favourites

Opioid activity of 4-imidazolidinone positional analogues of Leu-Enkephalin
pp. 3175-3178(4)
Authors: Rinnova, M.; Nefzi, A.; Houghten, R.A.

Favourites:Add to Favourites

New irreversible adenosine A1 antagonists based on FSCPX
pp. 3179-3182(4)
Authors: Beauglehole, A.R.; Baker, S.P.; Scammells, P.J.

Favourites:Add to Favourites

Retro-Binding thrombin active site inhibitors: identification of an orally active inhibitor of thrombin catalytic activity
pp. 3183-3186(4)
Authors: Iwanowicz, E.J.; Kimball, S.D.; Lin, J.; Lau, W.F.; Han, W.; Wang, T.C.; Roberts, D.G.M.; Schumacher, W.A.; Ogletree, M.L.; Seiler, S.M.

Favourites:Add to Favourites

Substituted uracil derivatives as potent inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)
pp. 3187-3190(4)
Authors: Steinhagen, H.; Gerisch, M.; Mittendorf, J.; Schlemmer, K.; Albrecht, B.

Favourites:Add to Favourites

Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity
pp. 3191-3193(3)
Authors: Ohki, H.; Hirotani, K.; Naito, H.; Ohsuki, S.; Minami, M.; Ejima, A.; Koiso, Y.; Hashimoto, Y.

Favourites:Add to Favourites

Dual NK1 antagonists-serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives
pp. 3195-3198(4)
Authors: Ryckmans, T.; Berton, O.; Grimee, R.; Kogej, T.; Lamberty, Y.; Pasau, P.; Talaga, P.; Genicot, C.

Favourites:Add to Favourites

P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease
pp. 3199-3202(4)
Authors: Priestley, E.S.; de Lucca, I.; Ghavimi, B.; Erickson-Viitanen, S.; Decicco, C.P.

Favourites:Add to Favourites

Two selective novel triterpene glycosides from sea cucumber, Telenata Ananas: inhibitors of chemokine receptor-5
pp. 3203-3205(3)
Authors: Hegde, V.R.; Chan, T.M.; Pu, H.; Gullo, V.P.; Patel, M.G.; Das, P.; Wagner, N.; Parameswaran, P.S.; Naik, C.G.

Favourites:Add to Favourites

An Efficient Protocol for Solution- and Solid-Phase End-Group Differentiation of Spermidine
pp. 3207-3208(2)
Authors: Silva, E.T.; Cunha, A.S.; Lima, E.L.S.

Favourites:Add to Favourites
Favourites:Add to Favourites

Identification and Structure-Activity Studies of Novel Ultrashort-Acting Benzodiazepine Receptor Agonists
pp. 3215-3218(4)
Authors: Stafford; Pacofsky; Cox, R.F.; Cowan, J.R.; Dorsey, G.F.; Gonzales, S.S.; Jung, D.K.; Koszalka, G.W.; McIntyre, M.S.; Tidwell, J.H.; Wiard, R.P.; Feldman, P.L.

Favourites:Add to Favourites

Relating the Structure, Activity, and Physical Properties of Ultrashort-Acting Benzodiazepine Receptor Agonists
pp. 3219-3222(4)
Authors: Pacofsky, G.J.; Stafford, J.A.; Cox, R.F.; Cowan, J.R.; Dorsey, G.F.; Gonzales, S.S.; Kaldor, I.; Koszalka, G.W.; Lovell, G.G.; McIntyre, M.S.; Tidwell, J.H.; Todd, D.; Whitesell, G.; Wiard, R.P.; Feldman, P.L.

Favourites:Add to Favourites
Favourites:Add to Favourites

Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors
pp. 3229-3233(5)
Authors: Sutton, J.C.; Bolton, S.A.; Hartl, K.S.; Huang, M.; Jacobs, G.; Meng, W.; Ogletree, M.L.; Pi, Z.; Schumacher, W.A.; Seiler, S.M.; Slusarchyk, W.A.; Treuner, U.; Zahler, R.; Zhao, G.; Bisacchi, G.S.

Favourites:Add to Favourites

Synthesis of potent and highly selective inhibitors of human tryptase
pp. 3235-3238(4)
Authors: Slusarchyk, W.A.; Bolton, S.A.; Hartl, K.S.; Huang, M.; Jacobs, G.; Meng, W.; Ogletree, M.L.; Pi, Z.; Schumacher, W.A.; Seiler, S.M.; Sutton, J.C.; Treuner, U.; Zahler, R.; Zhao, G.; Bisacchi, G.S.

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more