Publisher: Elsevier

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Volume 12, Number 11, 3 June 2002

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Graphical Abstracts
pp. ix-xv(7)

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Contributors to this Issue
pp. vii-viii(2)

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Novel lipoic acid analogues that inhibit nitric oxide synthase
pp. 1439-1442(4)
Authors: Harnett, J.J.; Auguet, M.; Viossat, I.; Dolo, C.; Bigg, D.; Chabrier, P.

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Design and synthesis of some new pyranoxanthenone aminoderivatives with cytotoxic activity
pp. 1443-1446(4)
Authors: Kolokythas, G.; Kostakis, I.K.; Pouli, N.; Marakos, P.; Skaltsounis, A.; Pratsinis, H.

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Glycosidation of alkylamino-alkan-1-ol. A simple and convenient synthesis of glycosylated cationic lipids
pp. 1447-1450(4)
Authors: Jacopin, C.; Egron, M.; Scherman, D.; Herscovici, J.

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CDP840. A prototype of a novel class of orally active anti-Inflammatory phosphodiesterase 4 inhibitors
pp. 1451-1456(6)
Authors: Alexander, R.P.; Warrellow, G.J.; Eaton, M.A.W.; Boyd, E.C.; Head, J.C.; Porter, J.R.; Brown, J.A.; Reuberson, J.T.; Hutchinson, B.; Turner, P.; Boyce, B.; Barnes, D.; Mason, B.; Cannell, A.; Taylor, R.J.; Zomaya, A.; Millican, A.; Leonard, J.; Morphy, R.; Wales, M.; Perry, M.; Allen, R.A.; Gozzard, N.; Hughes, B.; Higgs, G.

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Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor
pp. 1457-1461(5)
Authors: Guay, D.; Hamel, P.; Blouin, M.; Brideau, C.; Chan, C.C.; Chauret, N.; Ducharme, Y.; Huang, Z.; Girard, M.; Jones, T.R.; Laliberte, F.; Masson, P.; McAuliffe, M.; Piechuta, H.; Silva, J.; Young, R.N.; Girard, Y.

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Novel bicyclic oxazolone derivatives as anti-Angiogenic agents
pp. 1463-1466(4)
Authors: Perron-Sierra, F.M.; Pierre, A.; Burbridge, M.; Guilbaud, N.

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Cytotoxic alpha-Bromoacrylic derivatives of low molecular weight
pp. 1467-1471(5)
Authors: Beria, I.; Caldarelli, M.; Geroni, C.; Mongelli, N.; Reinach, B.; Vignati, L.; Cozzi, P.

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Identification of novel antifungal nonapeptides through the screening of combinatorial peptide libraries based on a hexapeptide motif
pp. 1473-1476(4)
Authors: Kundu, B.; Srinivasan, T.; Kesarwani, A.; Kavishwar, A.; Raghuwanshi, S.; Batra, S.; Shukla, P.

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SAR and species/stereo-selective metabolism of the sorbitol dehydrogenase inhibitor, CP-470,711
pp. 1477-1480(4)
Authors: Chu-Moyer, M.Y.; Ballinger, W.E.; Beebe, D.A.; Coutcher, J.B.; Day, W.W.; Li, J.; Oates, P.J.; Weekly, R.M.

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Structure-Activity studies for a novel series of tricyclic dihydropyrimidines as KATP channel openers (KCOs)
pp. 1481-1484(4)
Authors: Drizin, I.; Holladay, M.W.; Yi, L.; Zhang, H.Q.; Gopalakrishnan, S.; Gopalakrishnan, M.; Whiteaker, K.L.; Buckner, S.A.; Sullivan, J.P.; Carroll, W.A.

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Tricarbocyanine cholesteryl laurates labeled LDL: new near infrared fluorescent probes (NIRFs) for monitoring tumors and gene therapy of familial hypercholesterolemia
pp. 1485-1488(4)
Authors: Zheng, G.; Li, H.; Yang, K.; Blessington, D.; Licha, K.; Lund-Katz, S.; Chance, B.; Glickson, J.D.

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9-[(Hydroxymethyl)phenyl]adenines: new aryladenine substrates of adenosine deaminase1
pp. 1489-1492(4)
Authors: Brakta, M.; Murthy, D.; Ellis, L.; Phadtare, S.

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N-Tetrahydrofuroyl-(l)-phenylalanine derivatives as potent VLA-4 antagonists
pp. 1497-1500(4)
Authors: Yang, G.X.; Chang, L.L.; Truong, Q.; Doherty, G.A.; Magriotis, P.A.; de Laszlo, S.E.; Li, B.; MacCoss, M.; Kidambi, U.; Egger, L.A.; McCauley, E.; van Riper, G.; Mumford, R.A.; Schmidt, J.A.; Hagmann, W.K.

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Substituted tetrahydrofuroyl-1-phenylalanine derivatives as potent and specific VLA-4 antagonists
pp. 1501-1505(5)
Authors: Doherty, G.A.; Yang, G.X.; Borges, E.; Chang, L.L.; MacCoss, M.; Tong, S.; Kidambi, U.; Egger, L.A.; McCauley, E.; van Riper, G.; Mumford, R.A.; Schmidt, J.A.; Hagmann, W.K.

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Design, synthesis, and SAR of substituted acrylamides as factor Xa inhibitors
pp. 1511-1515(5)
Authors: Song, Y.; Clizbe, L.; Bhakta, C.; Teng, W.; Li, W.; Wu, Y.; Jia, Z.J.; Zhang, P.; Wang, L.; Doughan, B.; Su, T.; Kanter, J.; Woolfrey, J.; Wong, P.; Huang, B.; Tran, K.; Sinha, U.; Park, G.; Reed, A.; Malinowski, J.; Hollenbach, S.; Scarborough, R.M.; Zhu, B.

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Nicotinanilides as inhibitors of neutrophil chemotaxis
pp. 1517-1520(4)
Authors: Cutshall, N.S.; Kucera, K.A.; Ursino, R.; Latham, J.; Ihle, N.C.

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Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B
pp. 1521-1523(3)
Authors: Rajendran, V.; Saxena, A.; Doctor, B.P.; Kozikowski, A.P.

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Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors
pp. 1525-1528(4)
Authors: Naerum, L.; Norskov-Lauritsen, L.; Olesen, P.H.

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Doxorubicin immunoconjugates containing bivalent, lysosomally-Cleavable dipeptide linkages
pp. 1529-1532(4)
Authors: Dubowchik, G.M.; Radia, S.; Mastalerz, H.; Walker, M.A.; Firestone, R.A.; Dalton King, H.; Hofstead, S.J.; Willner, D.; Lasch, S.J.; Trail, P.A.

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Novel phthalimide derivatives, designed as leukotriene D4 receptor antagonists
pp. 1533-1535(3)
Authors: Lima, L.M.; de Brito, F.C.F.; de Souza, S.D.; Miranda, A.L.P.; Rodrigues, C.R.; Fraga, C.A.M.; Barreiro, E.J.

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CoMFA and HQSAR of acylhydrazide cruzain inhibitors
pp. 1537-1541(5)
Authors: Rodrigues, C.R.; Flaherty, T.M.; Springer, C.; McKerrow, J.H.; Cohen, F.E.

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Synthesis and cytotoxicity of 2α-amido docetaxel analogues
pp. 1543-1546(4)
Authors: Fang W.-S.; Liu, Y.; Liu, H.; Xu, S.; Wang, L.; Fang, Q.

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