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Publisher: Elsevier

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Volume 12, Number 5, 11 March 2002

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Graphical Abstracts
pp. ix-xv(7)

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Contributors to this Issue
pp. vii-viii(2)

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New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation
pp. 723-727(5)
Authors: Kolocouris, A.; Dimas, K.; Pannecouque, C.; Witvrouw, M.; Foscolos, G.B.; Stamatiou, G.; Fytas, G.; Zoidis, G.; Kolocouris, N.; Andrei, G.; Snoeck, R.; de Clercq, E.

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N-Aryl 2,6-Dimethoxybiphenylalanine Analogues as VLA-4 Antagonists
pp. 729-731(3)
Authors: Doherty, G.A.; Kamenecka, T.; McCauley, E.; van Riper, G.; Mumford, R.A.; Tong, S.; Hagmann, W.K.

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure-Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics
pp. 733-738(6)
Authors: Dragovich, P.S.; Prins, T.J.; Zhou, R.; Johnson, T.O.; Brown, E.L.; Maldonado, F.C.; Fuhrman, S.A.; Zalman, L.S.; Patick, A.K.; Matthews, D.A.; Hou, X.; Meador, J.W.; Ferre, R.A.; Worland, S.T.

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Anti-HIV-1 Activities and Pharmacokinetics of New Arylpiperazinyl Fluoroquinolones
pp. 739-742(4)
Authors: Ohmine, T.; Katsube, T.; Tsuzaki, Y.; Kazui, M.; Kobayashi, N.; Komai, T.; Hagihara, M.; Nishigaki, T.; Iwamoto, A.; Kimura, T.; Kashiwase, H.; Yamashita, M.

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Novel, Potent Non-Covalent Thrombin Inhibitors Incorporating P3-Lactam Scaffolds
pp. 743-748(6)
Authors: Ho, J.Z.; Gibson, T.S.; Semple, J.E.

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Anionic Cyclophanes as Potential Reversal Agents of Muscle Relaxants by Chemical Chelation
pp. 753-755(3)
Authors: Cameron, K.S.; Fielding, L.; Mason, R.; Muir, A.W.; Rees, D.C.; Thorn, S.; Zhang, M.

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Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 2: substituted benzo[a]cycloheptene derivatives
pp. 757-761(5)
Authors: Itani, H.; Ito, H.; Sakata, Y.; Hatakeyama, Y.; Oohashi, H.; Satoh, Y.

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Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa
pp. 763-766(4)
Authors: Renau, T.E.; Leger, R.; Yen, R.; She, M.W.; Flamme, E.M.; Sangalang, J.; Gannon, C.L.; Chamberland, S.; Lomovskaya, O.; Lee, V.J.

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Benzamide-Based Thiolcarbamates: A New Class of HIV-1 NCp7 Inhibitors
pp. 767-770(4)
Authors: Goel, A.; Mazur, S.J.; Fattah, R.J.; Hartman, T.L.; Turpin, J.A.; Huang, M.; Rice, W.G.; Appella, E.; Inman, J.K.

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Novel Agents Combining Platelet Activating Factor (PAF) Receptor Antagonist with Thromboxane Synthase Inhibitor (TxSI)
pp. 771-774(4)
Authors: Fujita, M.; Seki, T.; Inada, H.; Shimizu, K.; Takahama, A.; Sano, T.

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The Synthesis and Selective IL-2 Inhibitory Activity of Bis Piperazine-Phenol Mannich Adducts
pp. 775-778(4)
Authors: Geng, B.; Fleming, P.R.; Umlauf, S.; Lin, A.; Pallai, P.V.

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Synthesis and Activity of a New Methoxytetrahydropyran Derivative as Dual Cyclooxygenase-2/5-Lipoxygenase Inhibitor
pp. 779-782(4)
Authors: Barbey, S.; Goossens, L.; Taverne, T.; Cornet, J.; Choesmel, V.; Rouaud, C.; Gimeno, G.; Yannic-Arnoult, S.; Michaux, C.; Charlier, C.; Houssin, R.; Henichart J.-P.

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Synthesis and Vasorelaxant Activity of New Coumarin and Furocoumarin Derivatives
pp. 783-786(4)
Authors: Campos-Toimil, M.; Orallo, F.; Santana, L.; Uriarte, E.

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Potent nonsteroidal progesterone receptor agonists: Synthesis and SAR study of 6-aryl benzoxazines
pp. 787-790(4)
Authors: Zhang, P.; Terefenko, E.A.; Fensome, A.; Zhang, Z.; Zhu, Y.; Cohen, J.; Winneker, R.; Wrobel, J.; Yardley, J.

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Substituted 2-(R)-Methyl piperazines as muscarinic M2 selective ligands
pp. 791-794(4)
Authors: Kozlowski, J.A.; Zhou, G.; Tagat, J.R.; Lin, S.; McCombie, S.W.; Ruperto, V.B.; Duffy, R.A.; McQuade, R.A.; Crosby, G.; Taylor, L.A.; Billard, W.; Binch, H.; Lachowicz, J.E.

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Synthesis and structure-Activity relationships of M2-Selective muscarinic receptor ligands in the 1-[4-(4-Arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family
pp. 795-798(4)
Authors: McCombie, S.W.; Lin, S.; Tagat, J.R.; Nazareno, D.; Vice, S.; Ford, J.; Asberom, T.; Leone, D.; Kozlowski, J.A.; Zhou, G.; Ruperto, V.B.; Duffy, R.A.; Lachowicz, J.E.

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Novel Potent Antagonists of Human Neuropeptide Y Y5 Receptors. Part 3: 7-Methoxy-1-hydroxy-1-substituted Tetraline Derivatives
pp. 799-802(4)
Authors: Itani, H.; Ito, H.; Sakata, Y.; Hatakeyama, Y.; Oohashi, H.; Satoh, Y.

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Synthesis of Sordaricin Analogues as Potent Antifungal Agents against Candida albicans
pp. 803-806(4)
Authors: Kaneko, S.; Uchida, T.; Shibuya, S.; Honda, T.; Kawamoto, I.; Harasaki, T.; Fukuoka, T.; Konosu, T.

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Assamicin I and II, Novel Triterpenoid Saponins with Insulin-Like Activity from Aesculus assamica Griff.
pp. 807-810(4)
Authors: Sakurai, T.; Nishimura, T.; Otake, N.; Xinsheng, Y.; Abe, K.; Zeida, M.; Nagasawa, H.; Sakuda, S.

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Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. part 2:?
pp. 811-815(5)
Authors: Se Lee, B.; Chu, S.; Lee, B.; Yoon Chi, D.; Song, Y.S.; Jin, C.

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Synthesis and antiplatelet activity of gemfibrozil chiral analogues
pp. 817-821(5)
Authors: Ammazzalorso, A.; Amoroso, R.; Baraldi, M.; Bettoni, G.; Braghiroli, D.; de Filippis, B.; Duranti, A.; Moretti, M.; Tortorella, P.; Tricca, M.L.; Vezzalini, F.

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Cytotoxic, antifouling bromotyramines: A synthetic study on simple marine natural products and Their analogues
pp. 823-825(3)
Authors: Schoenfeld, R.C.; Conova, S.; Rittschof, D.; Ganem, B.

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2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: optimization of the tryptamine side chain
pp. 827-832(6)
Authors: Young, J.R.; Huang, S.X.; Walsh, T.F.; Wyvratt, M.J.; Yang, Y.T.; Yudkovitz, J.B.; Cui, J.; Mount, G.R.; Ren, R.N.; Wu, T.; Shen, X.; Lyons, K.A.; Mao, A.; Carlin, J.R.; Karanam, B.V.; Vincent, S.H.; Cheng, K.; Goulet, M.T.

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Structure-Activity relationships of oxime neurokinin antagonists: oxime modifications
pp. 833-836(4)
Authors: Reichard, G.A.; Spitler, J.; Aslanian, R.; Mutahi, M.; Shih, N.; Lin, L.; Ting, P.C.; Anthes, J.C.; Piwinski, J.J.

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