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Publisher: Elsevier

Volume 9, Number 17, 6 September 1999

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Human Telomerase Inhibition by Substituted Acridine Derivatives
pp. 2463-2468(6)
Authors: Harrison, R.J.; Gowan, S.M.; Kelland, L.R.; Neidle, S.

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6-Arylamino-5,8-Quinolinediones and 7-Arylamino-5,8-Isoquinolinediones as Inhibitors of Endothelium-Dependent Vasorelaxation
pp. 2469-2472(4)
Authors: Ryu, C.; Jung, S.; Lee, J.; Kim, H.; Lee, S.; Chung, J.

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Structure-Related Enhancing Activity of Escins Ia, Ib, IIa and IIb on Magnesium Absorption in Mice
pp. 2473-2478(6)
Authors: Li, Y.; Matsuda, H.; Wen, S.; Yamahara, J.; Yoshikawa, M.

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Versatile Fluorescence Labeling Method Using Activated Esters on Solid Support
pp. 2479-2482(4)
Authors: Chang, Y.; Schultz, P.G.

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Fluorobenzamidrazone Thrombin Inhibitors: Influence of Fluorine on Enhancing Oral Absorption
pp. 2483-2486(4)
Authors: Lee, K.; Jung, W.; Hwang, S.Y.; Lee, S.

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Synthesis and Phorbol Ester-Binding Studies of the Individual Cysteine-Rich Motifs of Protein Kinase D
pp. 2487-2490(4)
Authors: Irie, K.; Nakahara, A.; Ohigashi, H.; Fukuda, H.; Wender, P.A.; Konishi, H.; Kikkawa, U.

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2,7-Diazabicyclo[3.3.O]octanes as Novel h5-HT1D Receptor Agonists
pp. 2491-2496(6)
Authors: Russell, M.G.N.; Beer, M.S.; Stanton, J.A.; Sohal, B.; Mortishire-Smith, R.J.; Castro, J.L.

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The Design of Potent and Selective Inhibitors of Thrombin Utilizing a Piperazinedione Template: Part 1
pp. 2497-2502(6)
Authors: Cody, W.L.; Cai, C.; Doherty, A.M.; Edmunds, J.J.; He, J.X.; Narasimhan, L.S.; Plummer, J.S.; Rapundalo, S.T.; Rubin, J.R.; van Huis, C.A.; St-denis, Y.; Winocour, P.D.; Siddiqui, M.A.

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The Design of Potent and Selective Inhibitors of Thrombin Utilizing a Piperazinedione Template: Part 2
pp. 2503-2508(6)
Authors: Cody, W.L.; Augelli-Szafran, C.E.; Berryman, K.A.; Cai, C.; Doherty, A.M.; Edmunds, J.J.; He, J.X.; Narasimhan, L.S.; Penvose-Yi, J.; Plummer, J.S.; Rapundalo, S.T.; Rubin, J.R.; van Huis, C.A.; Leblond, L.; Winocour, P.D.; Siddiqui, M.A.

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A New Potent Inhibitor of Fungal Melanin Biosynthesis Identified Through Combinatorial Chemistry
pp. 2509-2514(6)
Authors: Jennings, L.D.; Wawrzak, Z.; Amorose, D.; Schwartz, R.S.; Jordan, D.B.

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Sodium Channel Activity and Sigma Binding of 2-Aminopropanamide Anticonvulsants
pp. 2521-2524(4)
Authors: Pevarello, P.; Bonsignori, A.; Caccia, C.; Amici, R.; McArthur, R.A.; Fariello, R.G.; Salvati, P.; Varasi, M.

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Synthesis and Antiviral Activity of Some N-Benzenesulphonylbenzimidazoles
pp. 2525-2530(6)
Authors: Garuti, L.; Roberti, M.; Cermelli, C.

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Synthesis and Structure Activity Relationships of Novel Small Molecule Cathepsin D Inhibitors
pp. 2531-2536(6)
Authors: Dumas, J.; Brittelli, D.; Chen, J.; Dixon, B.; Hatoum-Mokdad, H.; Konig, G.; Sibley, R.; Witowsky, J.; Wong, S.

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Dysidiolide and Related -Hydroxy Butenolide Compounds as Inhibitors of the Protein Tyrosine Phosphatase, Cdc25
pp. 2537-2538(2)
Authors: Blanchard, J.L.; Epstein, D.M.; Boisclair, M.D.; Rudolph, J.; Pal, K.

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Aminoisoquinolines: Design and Synthesis of an Orally Active Benzamidine Isostere for the Inhibition of Factor XA
pp. 2539-2544(6)
Authors: Choi-Sledeski, Y.M.; Becker, M.R.; Green, D.M.; Davis, R.; Ewing, W.R.; Mason, H.J.; Ly, C.; Spada, A.; Liang, G.; Cheney, D.; Barton, J.; Chu, V.; Brown, K.; Colussi, D.; Bentley, R.; Leadley, R.; Dunwiddie, C.; Pauls, H.W.

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Acylcarnitine Analogues as Topical, Microbicidal Spermicides
pp. 2545-2548(4)
Authors: Savle, P.S.; Doncel, G.F.; Bryant, S.D.; Hubieki, M.P.; Robinette, R.G.; Gandour, R.D.

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Synthesis and Sar of Thioester and Thiol Inhibitors of IMP-1 Metallo--Lactamase
pp. 2549-2554(6)
Authors: Greenlee, M.L.; Laub, J.B.; Balkovec, J.M.; Hammond, M.L.; Hammond, G.G.; Pompliano, D.L.; Epstein-Toney, J.H.

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Simple Mono-Derivatisation of the Aryl Moiety of d4A and ddA-Based Phosphoramidate Prodrugs Significantly Enhances their Anti-HIV Potency in Cell Culture
pp. 2555-2560(6)
Authors: Siddiqui, A.Q.; McGuigan, C.; Ballatore, C.; Wedgwood, O.; Clercq, E.D.; Balzarini, J.

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Protein Kinase C Modulators Bearing Dicarba-Closo-Dodecaborane as a Hydrophobic Pharmacophore
pp. 2561-2564(4)
Authors: Endo, Y.; Yoshimi, T.; Kimura, K.; Itai, A.

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A New Class of Selective and Potent Inhibitors of Neuronal Nitric Oxide Synthase
pp. 2569-2572(4)
Authors: Lowe, J.A.; Qian, W.; Volkmann, R.A.; Heck, S.; Nowakowski, J.; Nelson, R.; Nolan, C.; Liston, D.; Ward, K.; Zorn, S.; Johnson, C.; vanase, M.; Faraci, W.S.; Verdries, K.A.; Baxter, J.; Doran, S.; Sanders, M.; Ashton, M.; Whittle, P.; Stefaniak, M.

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Novel Benzo-Fused Lactam Scaffolds as Factor Xa Inhibitors
pp. 2573-2578(6)
Authors: Tamura, S.Y.; Goldman, E.A.; Bergum, P.W.; Semple, J.E.

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Isoquinoline-6-Carboxamides as Potent and Selective Anti-Human Cytomegalovirus (HCMV) Inhibitors
pp. 2583-2586(4)
Authors: Chan, L.; Jin, H.; Stefanac, T.; Wang, W.; Lavallee, J.; Bedard, J.; May, S.

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On Topography and Functionality in the B-D rings of Cephalostatin Cytotoxins
pp. 2587-2592(6)
Authors: LaCour, T.G.; Guo, C.; Ma, S.; Jeong, J.U.; Boyd, M.R.; Matsunaga, S.; Fusetani, N.; Fuchs, P.L.

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New Generation Dopaminergic Agents. 7. Heterocyclic Bioisosteres that Exploit the 3-OH-Phenoxyethylamine D2 Template
pp. 2593-2598(6)
Authors: Mewshaw, R.E.; Nelson, J.A.; Shah, U.S.; Shi, X.; Mazandarani, H.; Coupet, J.; Marquis, K.; Brennan, J.A.; Andree, T.H.

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BN 80927: A Novel Homocamptothecin with Inhibitory Activities on Both Topoisomerase I and Topoisomerase II
pp. 2599-2602(4)
Authors: Lavergne, O.; Harnett, J.; Rolland, A.; Lanco, C.; Lesueur-Ginot, L.; demarquay, D.; Huchet, M.; Coulomb, H.; Bigg, D.C.H.

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P'-Extended α-Ketoamide Inhibitors of Proteasome
pp. 2603-2606(4)
Authors: Chatterjee, S.; Dunn, D.; Mallya, S.; Ator, M.A.

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Quinoline-2,4-Dicarboxylic Acids: Synthesis and Evaluation as Inhibitors of the Glutamate Vesicular Transport System
pp. 2607-2612(6)
Authors: Carrigan, C.N.; Esslinger, C.S.; Bartlett, R.D.; Bridges, R.J.; Thompson, C.M.

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Identification and Initial Structure-Activity Relationships of a Novel Non-Peptide Quinolone GnRH Receptor Antagonist
pp. 2615-2620(6)
Authors: de Vita, R.J.; Hollings, D.D.; Goulet, M.T.; Wyvratt, M.J.; Fisher, M.H.; Lo, J.; Yang, Y.T.; Cheng, K.; Smith, R.G.

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Investigation of the 4-O-Alkylamine Substituent of Non-Peptide Quinolone GnRH Receptor Antagonists
pp. 2621-2624(4)
Authors: de Vita, R.J.; Goulet, M.T.; Wyvratt, M.J.; Fisher, M.H.; Lo, J.; Yang, Y.T.; Cheng, K.; Smith, R.G.

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Asymmetric Synthesis of Novel Quaternary α-Hydroxy--Lactam Dipeptide Surrogates
pp. 2625-2628(4)
Authors: Minami, N.K.; Reiner, J.E.; Semple, J.E.

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Facile Synthesis of N-Protected  and -Amino--Keto-Esters
pp. 2629-2634(6)
Authors: Li, B.; Franck, R.W.

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