Publisher: Elsevier

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Volume 5, Supplement 1, May 1997

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Optimisation of pharmaceutical formulations
pp. 6-6(1)
Author: Wehrleacute , P.

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Hydrogels for controlled oral drug delivery
pp. 7-7(1)
Authors: Hovgaard, L.; Broslashndsted, H.; Andersen, C.

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Use of hard gelatin capsules as rectal dosage forms
pp. 7-7(1)
Author: Eerikauml inen, S.

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Is there a need for time-controlled dosage forms
pp. 8-8(1)
Author: Marvola, M.

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Improving properties for direct compression
pp. 9-9(1)
Author: Bolhuis, G.K.

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Functional aspects of nicotinic receptors: native and recombinant
pp. 11-11(1)
Authors: Colquhoun, D.; Sivilotti, L.G.; McNeil, D.K.; Lewis, T.M.

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Potential roles of nicotinic receptor activation and desensitization in addiction to nicotine
pp. 12-12(1)
Authors: Collins, A.C.; Marks, M.J.; Grady, S.R.

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Studies of nicotinic receptors in human brain diseases
pp. 12-12(1)
Author: Nordberg, A.

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Behavioral sensitization to nicotine
pp. 13-13(1)
Authors: Engel, J.A.; Blomqvist, O.; Johnson, D.; Ericson, M.; Souml derpalm, B.

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Acute and chronic effects of nicotine on cerebral dopamine
pp. 13-13(1)
Authors: Ahtee, L.; Pietilauml , K.; Salminen, O.; Seppauml , T.

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Neuroprotective and therapeutic actions of nicotine
pp. 14-14(1)
Author: Sanberg, P.R.

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Behavioral effects of nicotine: focus on reward and social behavior; interactions with calcium antagonists
pp. 14-14(1)
Authors: Zvartau, E.E.; Kuzmin, A.V.; Patkina, N.A.; Belozertseva, I.V.

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Novel ligands of nicotinic receptors
pp. 15-15(1)
Author: Brioni, J.D.

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The role of cholinergic muscarinic and nicotinic receptors in the modulation of attention and memory
pp. 16-16(1)
Authors: Ruotsalainen, S.; MacDonald, E.; Sirviouml , J.

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Activation of penile nerves by nicotinic agonists
pp. 17-17(1)
Authors: Klinge, E.; Parkkisenniemi, U.; Alaranta, S.; Sjouml strand, N.O.

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Cotinine-nicotine interactions
pp. 17-17(1)
Authors: Tuominen, R.K.; Vainio, P.J.

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Human cell lines for the investigation of drug metabolism
pp. 19-19(1)
Authors: Magdalou, J.; Senay, C.; Terrier, N.; Sabolovic, N.; Fournel-Gigleux, S.

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Protein modelling in drug discovery
pp. 21-21(1)
Author: Johnson, M.S.

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Molecular modelling of H3 agonists and antagonists
pp. 22-22(1)
Author: Gynther, J.

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Approaches to design transition state analogs
pp. 23-23(1)
Author: Yliniemelauml , A.

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Drug permeation through pH- and thermo-responsive porous polymer membranes
pp. 26-26(1)
Authors: Aring kerman, S.; Viinikka, P.; Svarfvar, B.; Putkonen, K.; Kontturi, K.; Nauml sman, J.; Urtti, A.; Paronen, P.; Jauml rvinen, K.

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Linearity of the pharmacokinetics of a new anxiolytic compound deramciclane in dogs
pp. 26-26(1)
Authors: Kanerva, H.; Nevalainen, T.; Urtti, A.

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Spironolactone stability in solutions of [beta ]-cyclodextrin derivatives
pp. 26-26(1)
Authors: Kaukonen, A.M.; Kilpelauml inen, I.; Vuorela, H.; Mannermaa, J.

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3D QSAR of bile acid reabsorption inhibitors
pp. 27-27(1)
Authors: Baringhaus, K.; Matter, H.

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Phenotyping of pulmonary UDP-glucuronosyltransferase activity in lung cancer surgery patients
pp. 27-27(1)
Authors: Elovaara, E.; Luukkanen, L.; Anttila, S.; Vanhala, E.; Karjalainen, A.; Ikonen, T.; Ulmanen, I.; Vainio, H.

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Comparative molecular field analysis study of phosphodiesterase inhibitors
pp. 27-27(1)
Authors: Poso, A.; Ovaska, M.; Cockcroft, V.; Gynther, J.

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Evaluation of tablet surface homogeneity by computer-generated hologram method
pp. 30-30(1)
Authors: Ketolainen, J.; Silvennoinen, R.; Peiponen, K.; Suihko, E.; Paronen, P.

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The effects of some formulation and process variables on the properties of direct-compression diazepam tablets
pp. 30-30(1)
Authors: Pesonen, T.; Heinauml mauml ki, J.; Miettunen, T.; Antikainen, O.; Pohjola, J.; Yliruusi, J.

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Compression behaviour of tolbutamide/hydroxypropyl-[beta ]-cyclodextrin inclusion complex
pp. 30-30(1)
Authors: Korhonen, O.; Suihko, E.; Jauml rvinen, T.; Ketolainen, J.; Laine, E.; Paronen, P.

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Validation of sieve analysis system
pp. 30-30(1)
Authors: Kaukonen, J.; Nauml rvauml nen, T.

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Modification of drug release with calcium alginate forming Ex tempore in hard gelatin capsules
pp. 31-31(1)
Authors: Leik, I.; Ammon, I.; Juuml rjenson, H.; Veski, P.

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Approaches to design Panasorb[reg ] new drug form
pp. 31-31(1)
Author: Shikov, A.N.

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Some aspects granulation of a ginseng's extract in fluidized bed
pp. 31-31(1)
Authors: Shygarova, L.V.; Flisuk, H.V.; Minina, S.A.

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Characterisation of centrifugal granulating process of initial spherical beads based on microcrystalline cellulose
pp. 31-31(1)
Authors: Rashid, M.H.A.; Heinauml mauml ki, J.; Antikainen, O.; Yliruusi, J.

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Cyclodextrins in ophthalmic formulations of dipiverfin
pp. 32-32(1)
Authors: Jarho, P.; Urtti, A.; Stella, V.J.; Jauml rvinen, T.

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Orphan [alpha ]5 and [alpha ]6 subunits form functional nAChRs in human transfected cells
pp. 33-33(1)
Authors: Fucile, S.; Barabino, B.; Palma, E.; Ragozzino, D.; Grassi, F.; Ballivet, M.; Eusebi, F.

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The induction and loss of brain nicotine-receptor up-regulation after chronic nicotine in the drinking water to mice
pp. 33-33(1)
Authors: Pietilauml , K.; Lauml hde, T.; Ahtee, L.; Nordberg, A.

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Regional distribution of nicotinic receptors in human brain and effects of aging as characterized by [3H]-epibatidine
pp. 33-33(1)
Authors: Marutle, A.; Warpman, U.; Bogdanovic, N.; Nordberg, A.

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Deficits in neuronal nicotinic receptors in the Swedish 670671 mutation alzheimer family and sporadic alzheimer cases
pp. 34-34(1)
Authors: Warpman, U.; Marutle, A.; Bogdanovic, N.; Lannfelt, L.; Nordberg, A.

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Diazepam and nicotine gum: minor interaction on human performance
pp. 34-34(1)
Authors: Mattila, M.J.; Vanakoski, J.; Idauml npauml auml, n-

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Chronic ethanol treatment differently interacts with nicotinic and muscarinic receptor subtypes expressed in M10 and SH-SY5Y neuroblastoma cells
pp. 35-35(1)
Authors: Gorbounova, O.; Svensson, A.; Jouml nsson, P.; Mousavi, M.; Hellstrouml, m-; Nordberg, A.

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Nicotine and cotinine modulate eicosanoid synthesis in vitro
pp. 35-35(1)
Authors: Saareks, V.; Riutta, A.; Mucha, I.; Vapaatalo, H.

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Systemic nicotine induces Fos like immunoreactivity in the nucleus accumbens and medial prefrontal cortex by separate mechanisms
pp. 35-35(1)
Authors: Schilstrouml m, B.; Nomikos, G.G.; de Villiers, S.; Svensson, T.H.

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Opioid receptor subtype distribution in brains of alcohol-preferring and alcohol-avoiding rats
pp. 37-37(1)
Authors: Soini, S.L.; Ovaska, T.; Juurinen, S.; Honkanen, A.; Hyytiauml , P.; Korpi, E.R.

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Effects of repeated morphine administration on mesolimbic dopamine release in alcohol preferring aa and alcohol avoiding ana rats
pp. 37-37(1)
Authors: Piepponen, T.P.; Mikkola, J.; Honkanen, A.; Kiianmaa, K.; Ahtee, L.

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Debrisoquin and S-mephenytoin hydroxylation polymorphisms in a russian population living in estonia
pp. 38-38(1)
Authors: Marandi, T.; Dahl, M.L.; Rauml go, L.; Kiivet, R.A.; Sjouml qvist, F.

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Effects of the neuropeptide Y Y1 receptor antagonist bibp 3226 on food intake
pp. 38-38(1)
Authors: Kask, A.; Rauml go, L.; Harro, J.

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Pharmacological profiles of cerebellar gabaA receptors in [alpha ]6 subunit knockout and wild type mice
pp. 38-38(1)
Authors: Mauml kelauml , R.; Wisden, W.; Homanics, G.E.; Korpi, E.R.

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Pharmacological comparison of rat [rho ]1 [lsquo ]GABAC[rsquo ] receptors with rat hippocampal and crayfish GABAA receptors
pp. 38-38(1)
Authors: Wegelius, K.; Rivera, C.; Finckenberg, P.; Pasternack, M.

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Pharmacokinetics of different factor VIII preparations in haemophilia a patients
pp. 39-39(1)
Authors: Kallas, A.; Everaus, H.; Hinrikus, T.

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Glial cell line -derived neurotrophic factor system in rat penis
pp. 39-39(1)
Authors: Laurikainen, A.; Hiltunen, J.O.; Vanhatalo, S.; Klinge, E.; Saarma, M.

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Neuronal localization of ETB-receptors in the bovine retractor penis muscle
pp. 39-39(1)
Authors: Parkkisenniemi, U.; Palkama, A.; Klinge, E.

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1H-NMR conformational studies and molecular dynamics of selegiline derivatives
pp. 40-40(1)
Authors: Leppauml nen, J.; Nevalainen, T.; Laatikainen, R.; Poso, A.; Vepsauml lauml inen, J.; Kiuru, J.

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Molecular dynamics: comparison of the MD force fields
pp. 40-40(1)
Authors: Ropponen, R.; Cockcroft, V.; Hoffreacute n, A.; Kananen, M.; Savola, J.; Poso, A.; Gynther, J.

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Quantum chemical insight into protein phosphorylation
pp. 40-40(1)
Authors: Munck, N.; Paananen, A.; Taskinen, J.; Kunttu, H.

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Conformational analysis of three oligosaccharides related to the branch region of multivalent sLex Glycans
pp. 41-41(1)
Authors: Maaheimo, H.; Aitio, O.; Taskinen, J.; Renkonen, O.

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Structural characterization of E- and Z-entacapone glucuronides
pp. 41-41(1)
Authors: Luukkanen, L.; Taskinen, J.; Kilpelauml inen, I.; Ottoila, P.

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Influence of physicochemistry on the brain penetration of the triptans in the rat
pp. 41-41(1)
Authors: O'Connor, D.; Capel, C.; Rycroft, W.; Tattersall, D.; Sohal, B.; Graham, M.I.; Evans, D.C.

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Estimation of the aqueous solubility of drugs using artificial neural networks
pp. 41-41(1)
Authors: Huuskonen, J.; Salo, M.; Taskinen, J.

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Glucuronidation of nitrocatecholic COMT inhibitors by rat liver microsomes
pp. 42-42(1)
Authors: Lautala, P.; Kivimaa, M.; Salomies, H.; Elovaara, E.; Taskinen, J.

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Kinetic fluorometric assay for coumarin 7-hydroxylation
pp. 42-42(1)
Authors: Luoma, S.; Pasanen, M.; Juvonen, R.O.

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LC/MS-analysis of some catechol-type glucuronides from urine samples
pp. 42-42(1)
Authors: Keski-Hynnilauml , H.; Andersin, R.; Luukkanen, L.; Taskinen, J.; Kostiainen, R.

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Determination of entacapone glucuronides by micellar electrokinetic capillary chromatography
pp. 42-42(1)
Authors: Lehtonen, P.; Mauml lkki-Laine, L.; Wikberg, T.

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A GC-MS identification of novel ketamine metabolites
pp. 43-43(1)
Authors: Savchuk, S.A.; Brodsky, E.S.; Formanovsky, A.A.; Chistyakov, V.V.; Dolina, O.A.; Rudenko, B.A.

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The simultaneous determination of clodronate and its partial ester derivatives by ion-pair rp HPLC coupled with evaporative light-scattering detection
pp. 43-43(1)
Authors: Niemi, R.; Taipale, H.; Ahlmark, M.; Vepsauml lauml inen, J.; Jauml rvinen, T.

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Electrospray ionization mass spectrometry as a useful technique to elucidate the structure of complex ligands for histamine receptors
pp. 43-43(1)
Authors: Kovalainen, J.T.; Christiaans, J.A.M.; Poso, A.; Auriola, S.; Gynther, J.

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The x-ray diffraction of some gastrointestinal drugs
pp. 44-44(1)
Authors: Hinrikus, T.; Utsal, K.

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The choice of parameters in AMD (Automated Multiple Development) optimization
pp. 44-44(1)
Authors: Summanen, J.; Vuorela, H.; Hiltunen, R.

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New remote heterocyclic structural analogues of phenazone as potential anti-inflammatory drugs
pp. 44-44(1)
Authors: Lesyk, R.; Vladzimirska, O.; Nektegayev, I.; Pshyk, I.

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Development of HPLC methods for flavonoids in biological matrices
pp. 45-45(1)
Authors: Rauha, J.; Heinonen, M.; Hopia, A.; Vuorela, H.

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Spontaneous somatic embryo-genesis and plant regeneration of the medicinal plant angelica archangelica
pp. 45-45(1)
Authors: Kummala, T.; Vuorela, P.; Tammela, P.; Vuorela, H.; Hiltunen, R.

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Analysis of bio-active flavonoids in extracts of four epimedium species by micellar electrokinetic capillary chromatography
pp. 45-45(1)
Authors: Liang, H.R.; Vuorela, P.; Sireacute n, H.; Vuorela, H.; Riekkola, M.; Hiltunen, R.

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Isolation and identification of cyclopentene cyanohydrin bis-glycosides from three passiflora species
pp. 46-46(1)
Authors: Olafsdottir, E.S.; Thorgeirsdottir, E.; Jaroszewski, J.W.

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The x-ray diffractometric determination of some minerals of hyoscyamus niger
pp. 46-46(1)
Authors: Utsal, K.; Arak, E.; Raal, A.; Pudersell, K.

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Action of bearberry and pineapple-weed aqueous extracts on escherichia coli surface structures
pp. 46-46(1)
Authors: Annuk, H.; Arak, E.; Tuuml ri, E.; Tuuml ri, M.

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