Determination of hypnotic benzodiazepines (alprazolam, estazolam, and midazolam) and their metabolites in rat hair and plasma by reversed-phase liquid-chromatography with electrospray ionization mass spectrometry

Authors: Toyo'oka T.¹; Kumaki Y.; Kanbori M.; Kato M.; Nakahara Y.

Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 30, Number 6, 15 January 2003 , pp. 1773-1787(15)

Publisher: Elsevier

Keywords: Benzodiazepines; Hair analysis; Metabolic study; HPLC; Electrospray ionization mass spectrometry

Language: English

Document Type: Research article

DOI: 10.1016/S0731-7085(02)00520-4

Affiliations: 1: Department of Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, 422-8526, Shizuoka, Japan

Links for this article

http://www.ingentaconnect.com/els/07317085/2003/00000030/00000006/art00520
http://openurl.ingenta.com/content?genre=article&issn=0731-7085&volume=30&issue=6&spage=1773&epage=1787
http://dx.doi.org/10.1016/S0731-7085(02)00520-4