Development of a chiral assay for a novel, nonfluorinated quinolone, PGE-9509924, in dog plasma using high performance liquid chromatography with electrospray tandem mass spectrometry or fluorescence detection

Authors: Zoutendam P.H.; Canty J.F.; Martin M.J.; Dirr M.K.

Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 30, Number 1, 22 August 2002 , pp. 1-11(11)

Publisher: Elsevier

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Keywords: Chiral separation; FLEC; Derivatization; Nonfluorinated quinolone; Reverse phase chromatography; Electrospray HPLC/MS/MS; Fluorescence detection

Language: English

Document Type: Research article

DOI: http://dx.doi.org/10.1016/S0731-7085(01)00717-8

Affiliations: 1: Health Care Research Center, Procter and Gamble Pharmaceuticals Inc., 8700 Mason-Montgomery Road, 45040, Mason, OH, USA

Publication date: 2002-08-22

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