LC-1H NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems

Authors: Mortensen R.W.1; Corcoran O.; Cornett C.; Sidelmann U.G.; Troke J.; Lindon J.C.; Nicholson J.K.; Hansen S.H.

Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 24, Number 3, January 2001 , pp. 477-485(9)

Publisher: Elsevier

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Keywords: HPLC-NMR; Glucuronide; Acyl-migration; HPLC elution order; S-naproxen; Reactive metabolites

Language: English

Document Type: Research article

DOI: 10.1016/S0731-7085(00)00453-2

Affiliations: 1: aDepartment of Analytical and Pharmaceutical Chemistry, Royal Danish School of Pharmacy, 2, Universitetsparken, DK-2100 , Copenhagen, Denmark

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