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Publisher: Elsevier

Volume 1260, Number unknown, February 2004

Editorial Board
pp. iii-iii(1)

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Contents
pp. ix-xv(7)

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Preface
pp. v-v(1)
Authors: Nomura, Y.; Colson, L.

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Organizing committee
pp. vii-vii(1)

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Caloric restriction, gene expression and aging
pp. 13-20(8)
Author: Weindruch, R.

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The SAMP8 mouse as a model for Alzheimer disease: studies from Saint Louis University
pp. 23-28(6)
Authors: Morley, J.E.; Banks, W.A.; Kumar, V.B.; Farr, S.A.

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Quantitative trait loci for age-related memory dysfunction in SAMP8 and JF1 mice
pp. 29-34(6)
Authors: Isobe, M.; Tomobe, K.; Sawada, M.; Kondo, A.; Kurosawa, N.; Nomura, Y.

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Mouse senile amyloidosis in the SAM model
pp. 35-40(6)
Authors: Higuchi, K.; Xing, Y.; Fu, X.; Korenaga, T.; Guo, Z.; Nakamura, A.; Mori, M.

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Immune system deficiencies in SAM
pp. 41-46(6)
Author: Hosokawa, T.

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Age-related bone loss: lessons from the osteoporotic SAMP6 mouse model
pp. 55-60(6)
Authors: Jilka, R.L.; Shmookler Reis, R.J.; Manolagas, S.C.

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Pathobiological features in neurodegenerative diseases: an overview
pp. 69-75(7)
Authors: Higuchi, M.; Trojanowski, J.Q.; Lee, V.M.

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Pathological studies of neurodegeneration in SAMP10 mice
pp. 77-83(7)
Authors: Shimada, A.; Chiba, Y.; Kawamura, N.; Keino, H.; Hosokawa, M.

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Biochemical changes in the brain of the senescence-accelerated mouse P8 and P10
pp. 91-97(7)
Authors: Nomura, Y.; Okuma, Y.; Hosoi, T.; Nomura, J.

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Chemical intervention in senescence-accelerated mice metabolism for modeling neurodegenerative diseases: an overview
pp. 109-115(7)
Authors: Boldyrev, A.; Fedorova, T.; Stvolinsky, S.; Borras, C.; Sastre, J.; Vina, J.

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Ameliorative effects of dietary carotenoids on memory deficits in senescence-accelerated mice (SAMP8)
pp. 129-135(7)
Authors: Suganuma, H.; Hirano, T.; Kaburagi, S.; Hayakawa, K.; Inakuma, T.

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Ameliorative effects of nucleosides on senescence acceleration and memory deterioration in senescence-accelerated mice
pp. 143-149(7)
Authors: Kunii, D.; Wang, M.; Chan, Y.; Wong, Y.; Hosoda, K.; Yamamoto, S.

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Breeding system and background data for SAM mice at Japan SLC
pp. 153-160(8)
Authors: Suzuki, T.; Iida, M.; Masui, N.; Okudaira, S.; Shimizu, M.; Takagi, S.; Asai, H.

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Homepage of the Council for SAM Research (http://samrc.md.shinshu-u.ac.jp)
pp. 175-178(4)
Authors: Sawashita, J.; Higuchi, K.; Nakai, K.; Murase, S.; Hosokawa, M.; Miyamoto, M.; Akiguchi, I.; Takeda, T.

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Abnormal accumulation of corpora lutea in ovaries of the senescence accelerated mouse prone (SAMP1)
pp. 179-185(7)
Authors: Manabe, N.; Kiso, M.; Shimabe, M.; Nakai-Sugimoto, N.; Miyamoto, H.

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Genetic monitoring system for SAM strains utilizing DNA markers
pp. 187-190(4)
Authors: Mori, M.; Higuchi, K.

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Physiological characteristics in SAMP1 and SAMP2 mice
pp. 191-196(6)
Authors: Yanagidaira, Y.; Higuchi, K.

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Morphological changes of the thymus under stress caused by water immersion and restraint in SAMP1 mice
pp. 199-202(4)
Authors: Miyamoto, M.S.; Miyamoto, Y.; Hosokawa, T.

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The stability of interleukin-2 mRNA transcribed in splenic CD4+ T cells from SAMP1 mice
pp. 221-225(5)
Authors: Nishimura, Y.; Hosokawa, T.; Hosono, M.; Baba, M.; Iguchi, H.; Hosokawa, M.

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Expression of matrix metalloproteinases and their tissue inhibitors in ovaries of senescence accelerated mice
pp. 229-232(4)
Authors: Shimabe, M.; Manabe, N.; Kiso, M.; Komatsu, K.; Miyamoto, H.

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Expression of prolactin receptor mRNAs in ovaries of senescence accelerated mice
pp. 233-236(4)
Authors: Kiso, M.; Manabe, N.; Shimabe, M.; Komatsu, K.; Miyamoto, H.

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Mitochondrial alterations and a higher oxidative status in cultured fibroblast-like cells from senescence-accelerated mice
pp. 255-258(4)
Authors: Chiba, Y.; Yamashita, Y.; Hirayoshi, K.; Ueno, M.; Fujisawa, H.; Matsushita, T.; Kogishi, K.; Akiguchi, I.; Satoh, M.; Shimada, A.; Hosokawa, M.

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Microglial activation around amyloid- deposits in mouse and rat models
pp. 265-269(5)
Authors: Takata, K.; Kitamura, Y.; Tsuchiya, D.; Taniguchi, T.; Shimohama, S.

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Clearance of amyloid- in microglial culture model
pp. 271-274(4)
Authors: Tsuchiya, D.; Kitamura, Y.; Takata, K.; Taniguchi, T.; Shimohama, S.

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Neuroprotection against focal ischemia in the hyperbilirubinemic rat model
pp. 275-279(5)
Authors: Sugisaki, T.; Kitamura, Y.; Takata, K.; Taniguchi, T.

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Hemiparkinsonian rat models: different sensitivity of dopaminergic neurotoxins
pp. 281-285(5)
Authors: Kondo, J.; Kitamura, Y.; Inden, M.; Taniguchi, T.

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In vitro neurodegeneration model: dopaminergic toxin-induced apoptosis in human SH-SY5Y cells
pp. 287-290(4)
Authors: Nakamura, K.; Kitamura, Y.; Tsuchiya, D.; Inden, M.; Taniguchi, T.

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Parkinsonian model of planarian, an invertebrate flatworm
pp. 291-295(5)
Authors: Inden, M.; Kitamura, Y.; Taniguchi, T.; Watanabe, K.; Agata, K.

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Accelerated senescence and adaptation to cold exposure
pp. 299-302(4)
Authors: Yamashita, Y.; Chiba, Y.; Nakamura, E.; Hanai, A.; Matsuda, S.; Watanabe, T.; Deguchi, E.; Sato, M.; Shimada, A.; Hosokawa, M.

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Involvement of the glutamatergic system in behavioral disorders in senescence-accelerated mice (SAMP8)
pp. 303-308(6)
Authors: Fujiwara, Y.; Takahashi, H.; Hirai, K.; Miyamoto, M.

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Effects of rearing conditions on aging characteristics and pathobiological phenotypes in SAMP10 mice
pp. 315-319(5)
Authors: Kikumori, M.; Furukawa, S.; Araki, S.; Nishimura, T.; Nishimori, T.; Shimada, A.; Takeda, T.

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Age-related changes in hippocampal theta rhythm in SAMP8 mouse
pp. 321-324(4)
Authors: Sano, A.; Uezu, K.; Flood, J.F.; Farr, S.A.; Morley, J.E.; Uezu, E.; Sei, H.; Morita, Y.

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Deterioration in synaptic plasticity of cultured hippocampal neurons of senescence-accelerated mouse prone8
pp. 325-328(4)
Authors: Yang, S.; Zhang, H.; Qiao, H.; Liu, Z.; Zhou, W.; Zhang, Y.

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Age-related changes in telomere of brain cell in aging SAMP10 mice
pp. 329-333(5)
Authors: Wang, S.; Dong, C.; Lu, B.; Liu, J.

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Centripetal retraction of dendrites with apical vulnerability in the prefrontal neurons of aged SAMP10 mice
pp. 335-339(5)
Authors: Keino, H.; Shimada, A.; Tsuzuki, M.; Satoh, M.; Hosokawa, M.

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Age-related changes in blood-brain barrier of the SAM brain (2)
pp. 341-344(4)
Authors: Ueno, M.; Sakamoto, H.; Akiguchi, I.; Hosokawa, M.

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Genetic study of learning and memory deficits in SAMP8 mice
pp. 353-356(4)
Authors: Tomobe, K.; Isobe, M.; Sawada, M.; Okuma, Y.; Nomura, Y.

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Relationship between immune activity, senile amyloidosis and life span of hybrids of SAMP1 and B10.BR mice
pp. 357-361(5)
Authors: Toichi, E.; Matsushita, T.; Higuchi, K.; Hosokawa, T.; Hosokawa, M.; Hosono, M.

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Microarray analysis of mRNA expressed in colon of senescence-accelerated mouse P6
pp. 363-366(4)
Authors: Kawashima, T.; Shidoji, Y.; Oku, T.

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Expression of a novel gene containing ankyrin-repeat in SAMP8 mouse hippocampus
pp. 367-371(5)
Authors: Yamamura, N.; Koike, N.; Okuma, Y.; Uehara, T.; Nomura, Y.; Tashiro, T.; Sakaki, Y.; Furihata, C.

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Aging and acupuncture effects on hippocampal gene expression profile of SAMP10
pp. 379-382(4)
Authors: Han J.-x.; Ding, X.; Yu, J.; Yu, T.; Lu, M.; Wang, S.

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Induction of AApoAII and AA amyloidosis by the injections of various amyloid fibrils
pp. 383-386(4)
Authors: Fu, X.; Korenaga, T.; Xing, Y.; Fu, L.; Guo, Z.; Matsushita, T.; Hosokawa, M.; Naiki, H.; Mori, M.; Higuchi, K.

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Prevention of senile osteoporosis in SAMP6 mice by intra-bone marrow injection of allogeneic bone marrow cells
pp. 393-397(5)
Authors: Takada, K.; Inaba, M.; Ichioka, N.; Baba, S.; Taira, M.; Nakamura, K.; Iida, H.; Ikehara, S.

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Effects of Ganoderma on aging and learning and memory ability in senescence accelerated mice
pp. 399-404(6)
Authors: Wang M.-F.; Chan, Y.; Wu, C.; Wong, Y.; Hosoda, K.; Yamamoto, S.

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Neuroprotective effect of magnolol in the hippocampus of senescence-accelerated mice (SAMP1)
pp. 405-408(4)
Authors: Akagi, M.; Tada, T.; Shirono, A.; Fukuyama, Y.; Nakade, K.; Zhai, H.; Yasui, Y.; Akagi, R.

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Effects of dietary fats on senile amyloidosis in SAMP1 mice
pp. 427-431(5)
Authors: Umezawa, M.; Okuyama, H.; Hosokawa, M.; Takeda, T.; Higuchi, K.

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Characteristics of heme biosynthesis in the liver of the senescence-accelerated mouse
pp. 433-436(4)
Authors: Akagi, R.; Shimizu, R.; Koga, T.; Utsumi, A.; Watanabe, S.; Hanafusa, R.; Mori, M.

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Ameliorative effect of deep-sea water on biochemical and mechanical properties of bone in SAMP6 and SAMR1
pp. 437-440(4)
Authors: Iinuma, Y.; Motomura, K.; Miyagi, I.; Maehira, F.; Sudo, Y.

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Author index
pp. 441-443(3)

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Keyword index
pp. 445-448(4)

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