Mechanism of increased dissolution of diazepam and temazepam from polyethylene glycol 6000 solid dispersions

Authors: Verheyen S.; Blaton N.; Kinget R.; Van den Mooter G.1

Source: International Journal of Pharmaceutics, Volume 249, Number 1, 5 December 2002 , pp. 45-58(14)

Publisher: Elsevier

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Keywords: Solid dispersion; PEG6000; Benzodiazepines; Dissolution; Differential scanning calorimetry; X-ray powder diffraction; FT-IR spectroscopy; Solubility; GPC; Particle size determination

Language: English

Document Type: Research article

DOI: 10.1016/S0378-5173(02)00532-X

Affiliations: 1: Laboratorium voor Farmacotechnologie en Biofarmacie, K.U. Leuven, Campus Gasthuisberg O+N, Herestraat 49, 3000 , Leuven, Belgium

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