Physicochemical characterization and in vivo properties of Zolpidem in solid dispersions with polyethylene glycol 4000 and 6000

Authors: Trapani G.1; Franco M.; Latrofa A.; Pantaleo M.R.; Provenzano M.R.; Sanna E.; Maciocco E.; Liso G.

Source: International Journal of Pharmaceutics, Volume 184, Number 1, 5 July 1999 , pp. 121-130(10)

Publisher: Elsevier

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Keywords: Zolpidem; Solid dispersions; Physical mixtures; PEG 4000; PEG 6000; Water-solubility; Dissolution rate; Ataxic induction

Language: English

Document Type: Research article

DOI: 10.1016/S0378-5173(99)00112-X

Affiliations: 1: aDipartimento Farmaco-Chimico, Facolta di Farmacia, Universita degli Studi di Bari, Via Orabona 4, 70125, Bari, Italy

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