Application of the thermodynamics of mobile order and disorder to explain the solubility of temazepam in aqueous solutions of polyethylene glycol 6000

Authors: Van den Mooter G.1; Augustijns P.; Kinget R.

Source: International Journal of Pharmaceutics, Volume 164, Number 1, 13 April 1998 , pp. 81-89(9)

Publisher: Elsevier

Keywords: Temazepam; Solubility; Thermodynamics of mobile order and disorder

Language: English

Document Type: Research article

DOI: 10.1016/S0378-5173(97)00400-6

Affiliations: 1: Laboratorium voor Farmacotechnologie en Biofarmacie, Katholieke Universiteit Leuven, Campus Gasthuisberg O+N, Herestraat 49, B-3000 Leuven, Belgium

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