The interaction of human and bovine serum proteins with CYP3A in human liver microsomes: inhibition of testosterone 6beta-hydroxylation by albumin, alpha-globulins, alpha1-acid glycoprotein and gamma-globulins

Authors: Matsumoto S.; Ding L.R.; Ishii M.; Fischer N.E.; Inaba T.

Source: Toxicology Letters, Volume 136, Number 1, 15 November 2002 , pp. 33-41(9)

Publisher: Elsevier

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Keywords: CYP3A; Testosterone; Albumin; Globulins; alpha1-AGP

Language: English

Document Type: Research article

DOI: http://dx.doi.org/10.1016/S0378-4274(02)00285-0

Affiliations: 1: Department of Pharmacology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 8 Taddlecreek Road, , Ont., M5S 1A8, Toronto, Canada

Publication date: 2002-11-15

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