Statistical coassembly of glycine receptor α1 wildtype and the hyperekplexia mutant α1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system

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Keywords: Coexpression; Desensitization; Glycine receptor; Hyperekplexia; Ligand affinity; Subunit assembly; Whole-cell recording

Document Type: Short Communication


Affiliations: Institut fur Biochemie, Emil-Fischer-Zentrum, Friedrich-Alexander-Universitat Erlangen-Nurnberg, Fahrstrasse 17, D-91054 , Erlangen, Germany

Publication date: October 4, 2002

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