Publisher: Elsevier

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Volume 38, Number 4, April 2003

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Foreword
pp. 325-325(1)
Author: Lafont, O.

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Preface
pp. 327-327(1)
Author: Sanz, F.

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Biotechnology and applied genomics for health: initiatives of the European Union
pp. 329-337(9)
Authors: Aguilar, A.; Rainer, B.; Galetescu, L.; Donnelly, F.

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The design of potent, non-peptidic inhibitors of hepatitis C protease
pp. 339-343(5)
Authors: Andrews, D.M.; Chaignot, H.M.; Coomber, B.A.; Dowle, M.D.; Lucy Hind, S.; Johnson, M.R.; Jones, P.S.; Mills, G.; Patikis, A.; Pateman, T.J.; Ed Robinson, J.; Slater, M.J.; Trivedi, N.

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Inhibitors of phosphopantetheine adenylyltransferase
pp. 345-349(5)
Authors: Zhao, L.; Allanson, N.M.; Thomson, S.P.; Maclean, J.K.F.; Barker, J.J.; Primrose, W.U.; Tyler, P.D.; Lewendon, A.

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Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors
pp. 351-356(6)
Authors: Bruton, G.; Huxley, A.; O'Hanlon, P.; Orlek, B.; Eggleston, D.; Humphries, J.; Readshaw, S.; West, A.; Ashman, S.; Brown, M.; Moore, K.; Pope, A.; O'Dwyer, K.; Wang, L.

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Imidazolines as efficacious glucose-dependent stimulators of insulin secretion
pp. 357-362(6)
Authors: Jakobsen, P.; Madsen, P.; Andersen, H.

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Recent developments in the field of A2A and A3 adenosine receptor antagonists
pp. 367-382(16)
Authors: Baraldi, P.G.; Tabrizi, M.A.; Bovero, A.; Avitabile, B.; Preti, D.; Fruttarolo, F.; Romagnoli, R.; Varani, K.; Borea, P.A.

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Synthesis and HSA binding characterisation of the water soluble 7-succinylpaclitaxel
pp. 383-389(7)
Authors: Battaglia, A.; Bertucci, C.; Bombardelli, E.; Cimitan, S.; Guerrini, A.; Morazzoni, P.; Riva, A.

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Relative hydrophobicity and lipophilicity of drugs measured by aqueous two-phase partitioning, octanol-buffer partitioning and HPLC. A simple model for predicting blood-brain distribution
pp. 391-396(6)
Authors: Gulyaeva, N.; Zaslavsky, A.; Lechner, P.; Chlenov, M.; McConnell, O.; Chait, A.; Kipnis, V.; Zaslavsky, B.

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Impact of the aryl substituent kind and distance from pyrimido[2,1-f]purindiones on the adenosine receptor selectivity and antagonistic properties
pp. 397-402(6)
Authors: Drabczynska, A.; Schumacher, B.; Muller, C.E.; Karolak-Wojciechowska, J.; Michalak, B.; Pekala, E.; Kiec-Kononowicz, K.

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Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors
pp. 403-412(10)
Authors: Lopez-Rodrguez, M.L.; Viso, A.; Ortega-Gutierrez, S.; Fowler, C.J.; Tiger, G.; de Lago, E.; Fernandez-Ruiz, J.; Ramos, J.A.

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Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase
pp. 413-419(7)
Authors: Spadola, L.; Novellino, E.; Folkers, G.; Scapozza, L.

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A novel orally active inhibitor of HLE
pp. 421-425(5)
Authors: Varga, M.; Kapui, Z.; Batori, S.; Nagy, L.T.; Vasvari-Debreczy, L.; Mikus, E.; Urban-Szabo, K.; Aranyi, P.

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Prediction of oral bioavailability by adaptive fuzzy partitioning
pp. 427-431(5)
Authors: Pintore, M.; van de Waterbeemd, H.; Piclin, N.; Chretien, J.R.

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Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT2A and 5-HT2C receptor behaviours
pp. 433-440(8)
Authors: Brea, J.; Masaguer, C.F.; Villazon, M.; Isabel Cadavid, M.; Ravina, E.; Fontaine, F.; Dezi, C.; Pastor, M.; Sanz, F.; Isabel Loza, M.

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Nitric oxide-donating non-steroidal anti-inflammatory drugs: the case of nitroderivatives of aspirin
pp. 441-446(6)
Authors: Chiroli, V.; Benedini, F.; Ongini, E.; Del Soldato, P.

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Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists
pp. 447-449(3)
Authors: Frolund, B.; Tagmose, L.; Jorgensen, A.T.; Kristiansen, U.; Stensbol, T.B.; Liljefors, T.; Krogsgaard-Larsen, P.

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