Bone-specific delivery and sustained release of diclofenac, a non-steroidal anti-inflammatory drug, via bisphosphonic prodrug based on the Osteotropic Drug Delivery System (ODDS)

Authors: Hirabayashi H.1; Takahashi T.; Fujisaki J.; Masunaga T.; Sato S.; Hiroi J.; Tokunaga Y.; Kimura S.; Hata T.

Source: Journal of Controlled Release, Volume 70, Number 1, 29 January 2001 , pp. 183-191(9)

Publisher: Elsevier

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Keywords: Osteotropic drug delivery system; Biphosphonate; Prodrug; Diclofenac; Rat adjuvant

Language: English

Document Type: Research article

DOI: 10.1016/S0168-3659(00)00355-2

Affiliations: 1: aBiopharmaceutical and Pharmacokinetic Research Laboratories, Fujisawa Pharmaceutical Company, 1-6, Kashima 2-chome, Yodogawa-ku, 532-8514, Osaka, Japan

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