Tetracycline-HCl-loaded poly(dl-lactide-co-glycolide) microspheres prepared by a spray drying technique: influence of -irradiation on radical formation and polymer degradation

Authors: Bittner B.; Mader K.; Kroll C.; Borchert H.-H.; Kissel T.¹

Source: Journal of Controlled Release, Volume 59, Number 1, 1 May 1999 , pp. 23-32(10)

Publisher: Elsevier

Keywords: Poly(lactide-co-glycolide); Microspheres; Gamma-irradiation; Electron paramagnetic resonance spectroscopy (EPR); Tetracycline-HCl

Language: English

Document Type: Research article

DOI: 10.1016/S0168-3659(98)00170-9

Affiliations: 1: Department of Pharmaceutics and Biopharmacy, Philipps-University Marburg, Ketzerbach 63, D-35032 Marburg, Germany

Links for this article

http://www.ingentaconnect.com/els/01683659/1999/00000059/00000001/art00170
http://openurl.ingenta.com/content?genre=article&issn=0168-3659&volume=59&issue=1&spage=23&epage=32
http://dx.doi.org/10.1016/S0168-3659(98)00170-9