Tetracycline-HCl-loaded poly(dl-lactide-co-glycolide) microspheres prepared by a spray drying technique: influence of gamma-irradiation on radical formation and polymer degradation

Authors: Bittner B.; Mader K.; Kroll C.; Borchert H.-H.; Kissel T.1

Source: Journal of Controlled Release, Volume 59, Number 1, 1 May 1999 , pp. 23-32(10)

Publisher: Elsevier

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Keywords: Poly(lactide-co-glycolide); Microspheres; Gamma-irradiation; Electron paramagnetic resonance spectroscopy (EPR); Tetracycline-HCl

Language: English

Document Type: Research article

DOI: 10.1016/S0168-3659(98)00170-9

Affiliations: 1: Department of Pharmaceutics and Biopharmacy, Philipps-University Marburg, Ketzerbach 63, D-35032 Marburg, Germany

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