Synthesis of 2'-O-[2-[(N,N-dialkylamino)oxy]ethyl]-modified oligonucleotides: hybridization affinity, resistance to nuclease, and protein binding characteristics
Authors: Prakash, T.P.; Kawasaki, A.M.; Lesnik, E.A.; Sioufi, N.; Manoharan, M.
Source: Tetrahedron, Volume 59, Number 37, 8 September 2003 , pp. 7413-7422(10)
Document Type: Research Article
Affiliations: Department of Medicinal Chemistry, Isis Pharmaceuticals, Inc., 2280 Faraday Ave, 92008, Carlsbad, CA, USA
Publication date: 8 September 2003