Synthesis of a phosphotyrosyl analogue having chi1, chi2 and phgr angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue

Authors: Wang X.-Z.; Yao Z.-J.; Liu H.; Zhang M.; Yang D.; George C.; Burke T.R.

Source: Tetrahedron, Volume 59, Number 32, 4 August 2003 , pp. 6087-6093(7)

Publisher: Elsevier

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Keywords: phosphotyrosyl analogue; protein-tyrosine-kinase; SH2 domains

Language: English

Document Type: Research article

DOI: http://dx.doi.org/10.1016/S0040-4020(03)00978-5

Affiliations: 1: Laboratory of Medicinal Chemistry, Center for Cancer Research, National Cancer Institute, National Institutes of Health, NCI-Frederick, P.O. Box B, Bldg 376 Boyles St., 21702-1201, Frederick, MD, USA

Publication date: 2003-08-04

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