A general method for the asymmetric synthesis of both enantiomers of 1-substituted 1,2,3,4-tetrahydro--carbolines employing pyroglutamic acid derivatives as chiral auxiliaries

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Keywords: (S)-pyroglutamic acid; allyltributyltin; asymmetric addition; chiral auxiliary; indole alkaloid; silyl enol ether; -carboline

Document Type: Research Article

DOI: http://dx.doi.org/10.1016/S0040-4020(03)00420-4

Affiliations: School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan

Publication date: May 5, 2003

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