Simple and efficient syntheses of Boc- and Fmoc-protected 4(R)- and 4(S)-fluoroproline solely from 4(R)-hydroxyproline

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Keywords: 4(R)-hydroxyproline; 4-fluoroproline; Mitsunobu reaction; X-Ray analysis; collagen model peptides; stereoselective synthesis

Document Type: Research Article

DOI: http://dx.doi.org/10.1016/S0040-4020(02)01020-7

Affiliations: Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka Suita, 565-0871, Osaka, Japan

Publication date: October 14, 2002

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