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Asymmetric addition of nucleophiles to C-1 position of isoquinolines using (S)-alanine derivatives as chiral auxiliaries

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Keywords: 5,8-dibromoisoquinoline; alanine; allyltributyltin; asymmetric addition; chiral auxiliary; homolaudanosine; isoquinoline; silyl enol ether

Document Type: Research Article

DOI: http://dx.doi.org/10.1016/S0040-4020(01)00881-X

Affiliations: School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan

Publication date: October 15, 2001

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